Impact of dietary intake on brain choline levels: A 3 Tesla magnetic resonance spectroscopy study.

IF 1.7 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Saudi Medical Journal Pub Date : 2025-03-01 DOI:10.15537/smj.2025.46.3.20240698

Halima Hawesa, Mayar Alghumaiz, Renad Alghamdi, Nourah Alrabiah, Bayader Alfaifi, Hind Allam, Mahasin Gamalalddin, Haya Alshegri, Mansour Shanawani

{"title":"Impact of dietary intake on brain choline levels: A 3 Tesla magnetic resonance spectroscopy study.","authors":"Halima Hawesa, Mayar Alghumaiz, Renad Alghamdi, Nourah Alrabiah, Bayader Alfaifi, Hind Allam, Mahasin Gamalalddin, Haya Alshegri, Mansour Shanawani","doi":"10.15537/smj.2025.46.3.20240698","DOIUrl":null,"url":null,"abstract":"Objectives: To investigate the relationship between dietary choices and brain choline (Cho) levels using magnetic resonance spectroscopy (MRS).Methods: A total of 88 female students from the radiology department at King Abdullah bin Abdulaziz University Hospital, Riyadh, Saudi Arabia, participated in this study. Brain total choline (tCho) levels were estimated using MRS single volume sequence at a 3 Tesla field, with an echo time of 30 ms, repetition time of 2000 ms, voxel size of 15x15x15 mm, and water suppression bandwidth of 50 Hz. Participants' food consumption habits were assessed using a dietary questionnaire to quantify the amount of protein in their daily servings, as protein intake affects Cho levels in the brain.Results: Linear regression test applied using the Statistical Package for the Social Sciences, and the result showed significant impact of diet protein intake on the brain tCho level (p=0.000).Conclusion: The study's findings indicated that dietary choices significantly affect the levels of tCho in the brain. This research can serve as a baseline for health education, highlighting the close connection between dietary decisions and brain Cho levels. Understanding this relationship is essential for promoting a healthy lifestyle among younger generations.","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":"46 3","pages":"254-260"},"PeriodicalIF":1.7000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918667/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Saudi Medical Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.15537/smj.2025.46.3.20240698","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives: To investigate the relationship between dietary choices and brain choline (Cho) levels using magnetic resonance spectroscopy (MRS).

Methods: A total of 88 female students from the radiology department at King Abdullah bin Abdulaziz University Hospital, Riyadh, Saudi Arabia, participated in this study. Brain total choline (tCho) levels were estimated using MRS single volume sequence at a 3 Tesla field, with an echo time of 30 ms, repetition time of 2000 ms, voxel size of 15x15x15 mm, and water suppression bandwidth of 50 Hz. Participants' food consumption habits were assessed using a dietary questionnaire to quantify the amount of protein in their daily servings, as protein intake affects Cho levels in the brain.

Results: Linear regression test applied using the Statistical Package for the Social Sciences, and the result showed significant impact of diet protein intake on the brain tCho level (p=0.000).

Conclusion: The study's findings indicated that dietary choices significantly affect the levels of tCho in the brain. This research can serve as a baseline for health education, highlighting the close connection between dietary decisions and brain Cho levels. Understanding this relationship is essential for promoting a healthy lifestyle among younger generations.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Saudi Medical Journal 医学-医学：内科

CiteScore

2.30

自引率

6.20%

发文量

203

审稿时长

12 months

期刊介绍： The Saudi Medical Journal is a monthly peer-reviewed medical journal. It is an open access journal, with content released under a Creative Commons attribution-noncommercial license. The journal publishes original research articles, review articles, Systematic Reviews, Case Reports, Brief Communication, Brief Report, Clinical Note, Clinical Image, Editorials, Book Reviews, Correspondence, and Student Corner.