Ikram Tahani MD , Fadoua Achour MD , Noha El Ouafi Phd , Nabila Ismaili Phd
{"title":"An atypical multiple autoimmune syndrome: A case report including myocarditis","authors":"Ikram Tahani MD , Fadoua Achour MD , Noha El Ouafi Phd , Nabila Ismaili Phd","doi":"10.1016/j.radcr.2025.02.067","DOIUrl":null,"url":null,"abstract":"<div><div>The co-occurrence of autoimmune diseases has been epidemiologically studied and has contributed to our understanding of autoimmunity. The underlying mechanisms of this syndrome remain elusive; however, its prevalence may be higher than currently documented. The co-occurrence of at least 3 autoimmune diseases in a single patient has been defined as multiple autoimmune syndrome (MAS). This syndrome can be classified into 3 categories based on the prevalence of their associations with one another: type 1, type 2, and type 3. Myocarditis is classified as type 3, and typically does not present with connective tissue involvement. This report presents the case of a young female with known autoimmune disorders: rheumatoid arthritis (RA)and secondary Sjögren's syndrome (GSJ). The patient presented with MRI-confirmed myocarditis, likely of autoimmune origin, combining the 3 conditions in an atypical presentation. An additional noteworthy aspect of this case is the uncommon occurrence of myocarditis in rheumatoid arthritis, and even more so in Sjögren's syndromes.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 6","pages":"Pages 2806-2812"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1930043325001657","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
The co-occurrence of autoimmune diseases has been epidemiologically studied and has contributed to our understanding of autoimmunity. The underlying mechanisms of this syndrome remain elusive; however, its prevalence may be higher than currently documented. The co-occurrence of at least 3 autoimmune diseases in a single patient has been defined as multiple autoimmune syndrome (MAS). This syndrome can be classified into 3 categories based on the prevalence of their associations with one another: type 1, type 2, and type 3. Myocarditis is classified as type 3, and typically does not present with connective tissue involvement. This report presents the case of a young female with known autoimmune disorders: rheumatoid arthritis (RA)and secondary Sjögren's syndrome (GSJ). The patient presented with MRI-confirmed myocarditis, likely of autoimmune origin, combining the 3 conditions in an atypical presentation. An additional noteworthy aspect of this case is the uncommon occurrence of myocarditis in rheumatoid arthritis, and even more so in Sjögren's syndromes.
期刊介绍:
The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.