The Protective Effect of Low-Intensity Extremely-High-Frequency Electromagnetic Radiation on an Experimental Model of Intestinal Dysbiosis in Laboratory Rats

IF 4.033 Q4 Biochemistry, Genetics and Molecular Biology

Biophysics Pub Date : 2025-03-17 DOI:10.1134/S0006350924701252

A. B. Gapeyev, T. P. Kulagina, E. S. Zhukova, A. V. Aripovsky, M. A. Pozdnyakova

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引用次数: 0

Abstract

Using an experimental model of dysbiosis caused by the antibiotic gentamicin sulfate, the effect of low-intensity electromagnetic radiation of extremely high frequencies (42.2 GHz, 100 µW/cm², pulse modulation by a meander with a frequency of 1 Hz, exposure for 30 min per day for 10 consecutive days, starting from the 4th day after induction of dysbiosis) on the fatty acid composition of the thymus, blood plasma, activity of antioxidant enzymes, the content of malondialdehyde and lactate in the blood of laboratory rats was studied. A significant decrease in the content of myristic, palmitic, stearic, palmitoleic, oleic and linoleic fatty acids in the thymus of animals was shown. The activity of antioxidant enzymes, the content of fatty acids and malonic dialdehyde in the blood did not change. The content of lactate in the blood plasma decreased. Irradiation of animals with dysbiosis normalized the fatty acid composition of the thymus and the content of lactate in plasma. The high efficiency of low-intensity extremely-high-frequency electromagnetic radiation with certain parameters in dysbiosis opens up fundamentally new possibilities for using radiation in this range for the prevention and treatment of a number of pathological conditions associated with dysbiosis.

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来源期刊

Biophysics Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Biophysics is a multidisciplinary international peer reviewed journal that covers a wide scope of problems related to the main physical mechanisms of processes taking place at different organization levels in biosystems. It includes structure and dynamics of macromolecules, cells and tissues; the influence of environment; energy transformation and transfer; thermodynamics; biological motility; population dynamics and cell differentiation modeling; biomechanics and tissue rheology; nonlinear phenomena, mathematical and cybernetics modeling of complex systems; and computational biology. The journal publishes short communications devoted and review articles.