To assess the importance of bridges in road networks and achieve uniform traffic loss risk in seismic design, this paper introduces a novel bridge seismic design methodology incorporating the Seismic Importance Adjustment Factor (SIAF) and uniform traffic loss risk. The key technical contributions are as follows: (1) defining SIAF and developing an integrated framework that couples seismic design with traffic loss risk assessment; (2) proposing a calculation method for traffic loss risk that accounts for traffic demand variations during different periods of the day, uncertainties in post-earthquake bridge repair times, and dynamic traffic flow reassignment in post-earthquake road networks; (3) establishing design indicators for traffic loss risk and defining five seismic risk design levels based on historical disaster data; (4) validating the methodology through case studies on bridges and road networks, demonstrating how SIAF interconnects seismic design with risk-based design targets and adapt seismic design standards to varying network redundancies. The research demonstrates that SIAF can quantify bridge importance within complex road networks and provide a practical reference for the development of seismic design standards.