Double-Kissing Crush Versus Provisional Stenting for Coronary Bifurcations: A 1-Year Follow-up Study in Vietnam

Hai Nguyen Ngoc Dang MD , Thang Viet Luong MD , Nhut Cong Pham MD , Hieu Thi Nguyen Tran MD , Tien Anh Hoang MD, PhD , Binh Anh Ho MD, PhD , Thang Chi Doan MD, PhD , Hung Minh Nguyen MD, PhD
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Abstract

Background

Coronary bifurcation lesions (CBLs) present significant challenges in interventional cardiology, especially in low and middle-income countries like Vietnam. While the double-kissing (DK) crush technique is gaining attention for its potential benefits, its efficacy and safety compared with provisional stenting (PS) in the Vietnamese population remain underexplored. This study aimed to assess the effectiveness of the DK crush technique in reducing major adverse cardiovascular events (MACE) compared with those of PS, providing essential data to inform clinical decision-making in settings with limited resources.

Methods

This prospective cohort study included 58 patients with CBL, 33 patients undergoing the DK crush technique and 25 receiving PS. Clinical follow-up at 1, 3, 9, and 12 months assessed MACE, including cardiovascular disease–related death, acute myocardial infarction, hospitalization for heart failure, and stroke.

Results

Post-percutaneous coronary intervention side branch diameter stenosis in the DK crush group was 5.64% ± 5.80%, significantly lower than the PS group (48.2% ± 28.5%; P < .001). One-year follow-up data revealed greater MACE reduction in the DK crush group (91% MACE-free vs 72% in the PS group; P = .03; hazard ratio [HR], 3.689; 95% CI, 1.034-13.160). However, the DK crush technique had longer procedural times (91.1 vs 54.6 minutes) and required higher contrast and radiation doses (P < .01).

Conclusions

Although DK crush requires longer procedure times and greater radiation exposure, it results in greater MACE reduction than does PS in patients with CBL. Clinicians should weigh the benefits and limitations of both techniques, particularly in resource-limited settings.
背景冠状动脉分叉病变(CBL)给介入心脏病学带来了巨大挑战,尤其是在越南这样的中低收入国家。虽然双吻(DK)压碎技术因其潜在的优点而备受关注,但与临时支架置入术(PS)相比,该技术在越南人群中的有效性和安全性仍未得到充分探索。这项研究旨在评估与临时支架相比,DK压碎技术在减少主要不良心血管事件(MACE)方面的有效性,为资源有限情况下的临床决策提供重要数据。1、3、9和12个月的临床随访评估了MACE,包括心血管疾病相关死亡、急性心肌梗死、心力衰竭住院和中风。结果 经皮冠状动脉介入治疗后,DK压迫组的侧支直径狭窄率为5.64% ± 5.80%,明显低于PS组(48.2% ± 28.5%;P < .001)。一年的随访数据显示,DK压碎组的MACE减少率更高(91%无MACE,PS组为72%;P = .03;危险比[HR],3.689;95% CI,1.034-13.160)。结论虽然 DK 压碎术需要更长的手术时间和更大的辐射暴露,但与 PS 相比,它能更有效地减少 CBL 患者的 MACE。临床医生应权衡两种技术的优点和局限性,尤其是在资源有限的情况下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
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