Measuring static and dynamic lower limb alignment in patients with advanced knee osteoarthritis using markerless motion capture

IF 2.2 3区医学 Q3 NEUROSCIENCES

Gait & posture Pub Date : 2025-03-07 DOI:10.1016/j.gaitpost.2025.02.022

Jacob Calderone , Jereme Outerleys , Fernando Diaz Dilernia , Steve Mann , Gavin Wood , Kevin Deluzio , Elise Laende

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引用次数: 0

Abstract

Purpose

Marked lower limb malalignment is associated with the progression of knee osteoarthritis (OA). Markerless motion capture is a computer-vision tool that can measure lower limb alignment throughout both static and dynamic tasks.

Research questions

The primary objective of the study was to quantify static and dynamic lower limb alignment for patients diagnosed with advanced medial and lateral knee OA. This analysis also explored sex differences in alignment from the static and dynamic tasks. The secondary objective was to investigate if the mean knee adduction angle during quiet standing and the peak knee adduction angle during the first half of stance of gait were associated.

Methods

Ninety-two patients (37 male, 55 female) diagnosed with advanced knee OA (83 with predominantly medial knee OA, and 9 with predominantly lateral knee OA) completed a quiet standing task and a gait task for markerless motion capture using Theia3D software. Two-way analysis of variance tests were used to investigate sex differences and unpaired t-tests were computed to compare knee OA groups.

Results

Statistically significant differences in the knee adduction angle were found between medial and lateral knee OA groups during quiet standing (p < 0.001) and the first half of stance of gait (p < 0.0001). A strong correlation was found (Spearman’s ρ = 0.86, p < 0.0001) in lower limb alignment between the static and gait tasks.

Significance

These results show how markerless technology was able to quantify lower limb alignment and demonstrates potential for integration into clinic to assess musculoskeletal diseases.

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来源期刊

Gait & posture 医学-神经科学

CiteScore

4.70

自引率

12.50%

发文量

616

审稿时长

6 months

期刊介绍： Gait & Posture is a vehicle for the publication of up-to-date basic and clinical research on all aspects of locomotion and balance. The topics covered include: Techniques for the measurement of gait and posture, and the standardization of results presentation; Studies of normal and pathological gait; Treatment of gait and postural abnormalities; Biomechanical and theoretical approaches to gait and posture; Mathematical models of joint and muscle mechanics; Neurological and musculoskeletal function in gait and posture; The evolution of upright posture and bipedal locomotion; Adaptations of carrying loads, walking on uneven surfaces, climbing stairs etc; spinal biomechanics only if they are directly related to gait and/or posture and are of general interest to our readers; The effect of aging and development on gait and posture; Psychological and cultural aspects of gait; Patient education.