Outcome of obliterative versus reconstructive surgery for pelvic organ prolapse in women of advanced age − A propensity score analysis

IF 2.1 4区医学 Q2 OBSTETRICS & GYNECOLOGY

European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2025-03-14 DOI:10.1016/j.ejogrb.2025.03.033

Anna Padoa , Roni Tomashev , Matar Yekutiel , Hadil Hassouna , Liran Mendel , Tal Fligelman

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引用次数: 0

Abstract

Objective

Le Fort colpocleisis and reconstructive pelvic organ prolapse (POP) surgery in women aged ≥ 75 were compared. Evaluated outcomes were objective POP cure and long-term complications.

Study Design

We retrospectively identified patients aged > 75 following POP surgery during 2008–2021. Data were retrieved from clinical files. Objective cure was defined as POP stage < 2. Propensity score (PS) matching was used to balance background variables for outcomes of interest.

Results

108 women were identified. The PS-matched cohort for objective cure included 65 women and resulted in comparable cure rates: 18 (78.3%) vs 27 (64.3%) women, respectively (p = 0.375). Survival analysis demonstrated decreased rate of objective failure following Le Fort colpocleisis (HR = 0.52, 95% CI of [0.2138, 1.309], p = 0.20).

In the initial cohort, obliterative surgery resulted in more postoperative constipation. A PS model matched for constipation included 55 women and resulted in a trend to more constipation following Le Fort colpocleisis: 9 (40.9%) women vs 4 (13.8%) women, respectively (p = 0.06, SMD = 0.639).

Conclusion

Reconstructive POP surgery and Le Fort colpocleisis are equally effective in women of advanced age. POP recurrence may appear earlier following reconstructive surgery. Obliterative surgery may be related to more postoperative constipation.

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来源期刊

European journal of obstetrics, gynecology, and reproductive biology 医学-妇产科学

CiteScore

4.60

自引率

3.80%

发文量

898

审稿时长

8.3 weeks

期刊介绍： The European Journal of Obstetrics & Gynecology and Reproductive Biology is the leading general clinical journal covering the continent. It publishes peer reviewed original research articles, as well as a wide range of news, book reviews, biographical, historical and educational articles and a lively correspondence section. Fields covered include obstetrics, prenatal diagnosis, maternal-fetal medicine, perinatology, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine, infertility, reproductive endocrinology, sexual medicine and reproductive ethics. The European Journal of Obstetrics & Gynecology and Reproductive Biology provides a forum for scientific and clinical professional communication in obstetrics and gynecology throughout Europe and the world.