Daily profiles of nondrug reward and their association with daily outcomes for people in recovery from opioid use disorder: An application of latent profile analysis applied to intensive longitudinal data

IF 3.9 2区医学 Q1 PSYCHIATRY

Drug and alcohol dependence Pub Date : 2025-03-08 DOI:10.1016/j.drugalcdep.2025.112646

Samuel W. Stull , Lisa A. Marsch , Stephanie T. Lanza

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引用次数: 0

Abstract

Introduction

Daily rewarding experiences not involving drugs are complex and may differentially support recovery from addiction. Rarely has nondrug reward, and its multiple facets (i.e. anticipation, meaning etc.), been examined in daily life—this could uncover the acute benefits of different components of nondrug reward on daily recovery outcomes.

Methods

153 adults in recovery from OUD receiving opioid agonist treatment (M age=41.1, SD=9.5; 57 % women; 84 % white) completed daily diaries for three weeks (2067 person-days), answering 7 continuous items about appraisals of nondrug rewards (e.g., meaning, reward, and anticipation). Item responses were used as indicators in a latent profile analysis. Daily latent profiles of nondrug reward were tested for their association with recovery outcomes (quality of life, mood, craving and use) using robust standard errors to adjust for the multilevel data structure.

Results

The selected model had four latent profiles (% of days): Highly Anticipated-Rewarding (35 %), Moderately Rewarding (31 %), Minimally Rewarding-Unplanned (22 %), and Highly Rewarding-Unplanned profile (12 %). Relative to the Moderately Rewarding profile, Highly Anticipated-Rewarding was associated with greater positive mood and quality of life and lower negative mood and low-arousal moods. People with more days in the Highly Anticipated-Rewarding Profile (vs. Moderately Rewarding) were less likely to use or crave opioids.

Conclusion

Greater meaning, reward, and anticipation (including planning) across indicators within profiles were associated with the best recovery outcomes. Latent profile analysis applied to intensive longitudinal data offers an innovative methodological approach for simultaneously assessing multiple daily protective factors that together may differentially promote recovery.

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阿片类药物使用障碍患者非药物奖励的日常概况及其与日常结果的关系：应用于密集纵向数据的潜在概况分析

不涉及药物的日常奖励体验是复杂的，可能不同地支持从成瘾中恢复。在日常生活中很少有非药物奖励及其多个方面（即预期，意义等）被检查-这可以揭示非药物奖励的不同组成部分对日常恢复结果的急性益处。方法153例接受阿片受体激动剂治疗的OUD恢复期成人(M年龄=41.1，SD=9.5；57%的女性；84%白人)完成了为期三周（2067人日）的每日日记，回答了7个关于非药物奖励评估的连续项目（例如，意义，奖励和预期）。项目反应被用作潜在剖面分析的指标。非药物奖励的每日潜在特征与恢复结果（生活质量、情绪、渴望和使用）的关系进行了测试，使用稳健的标准误差来调整多层次数据结构。结果所选模型有四种潜在特征（占天数的%）：高期望-奖励（35%），中等奖励（31%），最低奖励-计划外（22%）和高奖励-计划外（12%）。相对于适度奖励，高期望奖励与更积极的情绪和生活质量以及更低的消极情绪和低唤醒情绪相关。处于高预期奖励状态（与中等奖励相比）的人更不可能使用或渴望阿片类药物。结论更大的意义、奖励和预期（包括计划）与剖面内指标的最佳恢复结果相关。潜在剖面分析应用于密集的纵向数据，提供了一种创新的方法方法，可以同时评估多种日常保护因素，这些因素加在一起可能会不同地促进恢复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Drug and alcohol dependence 医学-精神病学

CiteScore

7.40

自引率

7.10%

发文量

409

审稿时长

41 days

期刊介绍： Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.