Clinical efficacy of allograft bone combined with calcium phosphate bone powder in repairing bone defects of benign bone tumors: A retrospective controlled study.

IF 1.6 3区 医学 Q2 SURGERY
Qiang Liu, Jianping Zheng, Long Ma, Dawei Chu, Zongqiang Yang, Ningkui Niu, Jiandang Shi
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Abstract

Objective: To evaluate the clinical efficacy of repairing bone defects caused by benign bone tumors using allograft bone combined with calcium phosphate bone powder.

Methods: A retrospective analysis was conducted on 55 patients (aged 10-61 years, mean 35 ± 13.2) with benign bone tumors treated at our hospital from June 2020 to December 2022. The bone defects in these cases were created after surgical curettage of the tumor lesions, which included common benign tumors such as osteochondroma, giant cell tumor of bone, and enchondroma. Patients were divided into two groups based on bone graft materials: a simple allograft bone group (n = 30) and a combined group using allograft bone with calcium phosphate bone powder (n = 25). Preoperative data, surgical time, intraoperative blood loss, postoperative complications, imaging findings, limb function, and quality of life (KPS scores) were analyzed.

Results: All 55 patients were followed for 12-30 months (mean 13.45 ± 5.18). All incisions healed by primary intention without complications such as graft nonunion, fractures, or tumor recurrence. The combined group showed a significantly shorter healing time (t = 4.280, P < 0.05) and higher KPS scores at 6 months postoperatively (X2 = 3.646, P < 0.05) compared to the simple group. However, no significant differences were observed between groups in healing rate, residual bone defects, or limb function at 12 months postoperatively (P > 0.05).

Conclusion: Allograft bone combined with calcium phosphate bone powder is superior to allograft bone alone for repairing bone defects following curettage of benign bone tumors, promoting faster healing and better postoperative functional recovery.

异体骨联合磷酸钙骨粉修复良性骨肿瘤骨缺损的回顾性对照研究。
目的:评价同种异体骨联合磷酸钙骨粉修复良性骨肿瘤所致骨缺损的临床疗效。方法:回顾性分析2020年6月至2022年12月我院收治的55例骨良性肿瘤患者(年龄10 ~ 61岁,平均35±13.2岁)的临床资料。这些病例的骨缺损是在手术刮除肿瘤病变后产生的,包括常见的良性肿瘤,如骨软骨瘤、骨巨细胞瘤和内软骨瘤。根据骨移植材料将患者分为两组:单纯同种异体骨移植组(n = 30)和同种异体骨与磷酸钙骨粉联合组(n = 25)。分析术前资料、手术时间、术中出血量、术后并发症、影像学表现、肢体功能和生活质量(KPS评分)。结果:55例患者随访12 ~ 30个月(平均13.45±5.18)。所有切口均按原意愈合,无移植物不连、骨折或肿瘤复发等并发症。联合治疗组愈合时间明显缩短(t = 4.280, P 2 = 3.646, P 0.05)。结论:同种异体骨联合磷酸钙骨粉修复良性骨肿瘤刮除后骨缺损优于单用同种异体骨,愈合更快,术后功能恢复更好。
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来源期刊
BMC Surgery
BMC Surgery SURGERY-
CiteScore
2.90
自引率
5.30%
发文量
391
审稿时长
58 days
期刊介绍: BMC Surgery is an open access, peer-reviewed journal that considers articles on surgical research, training, and practice.
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