Long-term follow-up after ureteral reimplantation in children: a 12-year analysis.

IF 1.5 3区 医学 Q2 PEDIATRICS
T Gerwinn, M Zellner, A Prouza, U Kennedy, M Horst, L Mazzone
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引用次数: 0

Abstract

Purpose: To evaluate the incidence of late surgical complications and long-term kidney outcomes following ureteral reimplantation (UR) for high-grade vesicoureteral reflux (VUR) and primary obstructed megaureter (POM), assessing the necessity of routine long-term follow-up.

Methods: A retrospective review was conducted of 135 children who underwent UR between 2006 and 2013, with at least 10 years of follow-up. Primary outcomes included postoperative ureterovesical junction obstruction (pUVJO) and febrile urinary tract infections (UTIs). Secondary outcomes assessed kidney function and morphology (renal ultrasound changes, elevated BUN/creatinine, and arterial hypertension).

Results: Fifty-three renal units in 34 children met the inclusion criteria. pUVJO occurred in 7.5% of units, exclusively after Politano-Leadbetter (P-L) reimplantation, and within eight months postoperatively. Nine children experienced febrile UTIs, primarily within the first postoperative year. One child with reflux nephropathy (RN) developed chronic kidney disease 12 years later, and another developed RN without impaired function. No hypertension was observed in the cohort.

Conclusion: Children with uneventful recoveries and no pUVJO in the first year have a low risk of late complications, suggesting limited benefit from routine long-term follow-up. Higher risk groups, including those undergoing P-L reimplantation, girls, and those with preoperative RN, may warrant extended follow-up.

儿童输尿管再植术后的长期随访:12年分析。
目的:评价输尿管再植术(UR)治疗高级别膀胱输尿管反流(VUR)和原发性梗阻性血液计(POM)术后晚期手术并发症的发生率和长期肾脏预后,评估常规长期随访的必要性。方法:回顾性分析2006 - 2013年间135例UR患儿,随访至少10年。主要结局包括术后输尿管膀胱交界处梗阻(pUVJO)和发热性尿路感染(UTIs)。次要结果评估肾功能和形态(肾脏超声改变、BUN/肌酐升高和动脉高血压)。结果:34例患儿53个肾单位符合纳入标准。7.5%的单位发生pUVJO,仅在Politano-Leadbetter (P-L)再植后和术后8个月内发生。9名儿童出现发热性尿路感染,主要发生在术后第一年。一名患有反流性肾病(RN)的儿童在12年后发展为慢性肾病,另一名儿童发展为无功能受损的RN。该队列中未观察到高血压。结论:患儿康复平稳,第一年无pUVJO,晚期并发症风险低,提示常规长期随访获益有限。高危人群,包括行P-L再植、女孩和术前RN患者,可能需要延长随访时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.00
自引率
5.60%
发文量
215
审稿时长
3-6 weeks
期刊介绍: Pediatric Surgery International is a journal devoted to the publication of new and important information from the entire spectrum of pediatric surgery. The major purpose of the journal is to promote postgraduate training and further education in the surgery of infants and children. The contents will include articles in clinical and experimental surgery, as well as related fields. One section of each issue is devoted to a special topic, with invited contributions from recognized authorities. Other sections will include: -Review articles- Original articles- Technical innovations- Letters to the editor
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