Assessment of malaria treatment interventions: a critical analysis of government initiatives and causes of treatment failure at Port Loko Government Hospital, Sierra Leone.

IF 2.4 3区 医学 Q3 INFECTIOUS DISEASES
Lawrence Sao Babawo, Rashid Bundu Kpaka, Daniel Karim Dauda Sesay
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Abstract

Background: Malaria remains a significant public health challenge, particularly in sub-Saharan Africa, where it accounts for high morbidity and mortality rates. Sierra Leone, including Port Loko District, continues to experience a high burden of malaria despite government interventions. This study evaluates the existing government interventions for malaria treatment at Port Loko Government Hospital, examining the socio-economic determinants contributing to malaria treatment failure.

Methods: The study employed a cross-sectional study design with a quantitative approach, involving 150 health workers and 150 women of childbearing age. A purposive stratified random sampling technique was used to ensure diverse representation. Primary data were collected using structured questionnaires, while secondary data were extracted from the District Health Information System (DHIS) and hospital records. Data were analysed using SPSS version 28.0, applying descriptive statistics (frequencies, percentages, means and SD) and inferential analyses (Chi-square tests and binary logistic regression) to assess associations between socio-economic factors and treatment-seeking behaviours.

Results: Findings revealed that 90% of health workers were aware of malaria interventions, but only 68% reported high adherence to treatment guidelines. Among women of childbearing age, 40% sought malaria treatment at drug stores or pharmacies due to financial constraints, and a significant association was observed between socio-economic status and healthcare-seeking behaviour (2 = 9.32, df = 4, p = 0.05). Despite the fact that 73.3% reported the use of long-lasting insecticidal nets (LLINs), malaria prevalence remained high, suggesting additional risk factors beyond bed net usage.

Conclusion: This study highlighted persistent challenges in malaria control, including inadequate healthcare access, non-adherence to treatment regimens, and socio-economic constraints. Policy recommendations include strengthening malaria treatment adherence programmes, improving healthcare accessibility, and enhancing community-based malaria prevention strategies.

疟疾治疗干预措施评估:对塞拉利昂洛科港政府医院的政府举措和治疗失败原因的批判性分析。
背景:疟疾仍然是一项重大的公共卫生挑战,特别是在撒哈拉以南非洲,它造成了高发病率和高死亡率。尽管政府采取了干预措施,塞拉利昂,包括洛科港区,仍然承受着很高的疟疾负担。本研究评估了Loko港政府医院现有的疟疾治疗政府干预措施,审查了导致疟疾治疗失败的社会经济决定因素。方法:本研究采用横断面研究设计和定量方法,涉及150名卫生工作者和150名育龄妇女。采用有目的的分层随机抽样技术,以确保多样化的代表性。主要数据采用结构化问卷收集,次要数据来自地区卫生信息系统(DHIS)和医院记录。数据分析采用SPSS 28.0版,采用描述性统计(频率、百分比、均值和SD)和推理分析(卡方检验和二元逻辑回归)来评估社会经济因素与寻求治疗行为之间的关联。结果:调查结果显示,90%的卫生工作者了解疟疾干预措施,但只有68%的卫生工作者报告高度遵守了治疗指南。在育龄妇女中,由于经济拮据,40%到药店或药房寻求疟疾治疗,社会经济地位与寻求保健行为之间存在显著关联(2 = 9.32,df = 4, p = 0.05)。尽管有73.3%的人报告使用了长效杀虫蚊帐,但疟疾流行率仍然很高,这表明除使用蚊帐外还有其他危险因素。结论:本研究突出了疟疾控制方面的持续挑战,包括医疗保健服务不足、不遵守治疗方案以及社会经济制约。政策建议包括加强疟疾治疗依从性规划,改善卫生保健可及性,以及加强基于社区的疟疾预防战略。
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来源期刊
Malaria Journal
Malaria Journal 医学-寄生虫学
CiteScore
5.10
自引率
23.30%
发文量
334
审稿时长
2-4 weeks
期刊介绍: Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialities involved in this very broad discipline, from the bench to the bedside and to the field.
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