Abigail McCay, Odinaka Onuigbo, MaCee Boyle, Sahla Esam, Shreya Gaddipati, Charles B Chen, Sanu Yadav, Akshaya Vachharajani
{"title":"Sequential direct bilirubin values in preterm infants.","authors":"Abigail McCay, Odinaka Onuigbo, MaCee Boyle, Sahla Esam, Shreya Gaddipati, Charles B Chen, Sanu Yadav, Akshaya Vachharajani","doi":"10.1038/s41372-025-02264-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>We aim to describe sequential direct bilirubin levels in preterm infants and examine the outcomes of subsequent evaluation of direct hyperbilirubinemia.</p><p><strong>Study design: </strong>Retrospective electronic chart analysis of preterm infants admitted and surviving the neonatal intensive care unit (NICU) stay was performed.</p><p><strong>Result: </strong>A total of 127 preterm infants had 665 bilirubin measurements (333 direct bilirubin; 332 total bilirubin) during their first NICU stay. Before five days of age, twenty-seven (27/127, 21%) infants had abnormal direct bilirubin estimations. At fourteen days, three of these infants (3/27, 11%) had abnormal values. All three infants had further testing and more direct bilirubin estimations than their cohort. All infants had normal levels by discharge. Age-appropriate direct bilirubin values were based on those described by Feldman et al. CONCLUSION: All preterm infants with elevated direct bilirubin had normal values by discharge.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Perinatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41372-025-02264-7","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: We aim to describe sequential direct bilirubin levels in preterm infants and examine the outcomes of subsequent evaluation of direct hyperbilirubinemia.
Study design: Retrospective electronic chart analysis of preterm infants admitted and surviving the neonatal intensive care unit (NICU) stay was performed.
Result: A total of 127 preterm infants had 665 bilirubin measurements (333 direct bilirubin; 332 total bilirubin) during their first NICU stay. Before five days of age, twenty-seven (27/127, 21%) infants had abnormal direct bilirubin estimations. At fourteen days, three of these infants (3/27, 11%) had abnormal values. All three infants had further testing and more direct bilirubin estimations than their cohort. All infants had normal levels by discharge. Age-appropriate direct bilirubin values were based on those described by Feldman et al. CONCLUSION: All preterm infants with elevated direct bilirubin had normal values by discharge.
期刊介绍:
The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development.
The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.