Outcomes of spontaneous pneumothorax in neonates: treatments vs. expectant management.

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2025-03-15 DOI:10.1038/s41372-025-02259-4

Anat Margaliot, Laurence Mangel, Yarden Waxman, Moria Be'er, Ronella Marom, Jacky Herzlich

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引用次数: 0

Abstract

Background: Neonatal pneumothorax is dependent on severity of symptoms and leak size. Treatment of Pneumothorax with Nitrogen washout is controversial.

Objective: To compare outcomes of neonates treated for spontaneous pneumothorax (SP) compared with those managed expectantly.

Methods: A retrospective review of medical records of neonates (≥34weeks) diagnosed with SP born between 2011 and 2021. Neonatal characteristics and outcomes were compared between neonates treated for SP with either targeted oxygen therapy (to stabilize saturation ≥93%) or nitrogen washout and those under expectant management.

Results: Among neonates with respiratory distress and desaturation (n = 64), nitrogen washout reduced median time to resolution compared to targeted oxygen therapy (31 [12-67] vs 81 [31.8-123.5] hours, p = 0.012). Expectantly managed neonates with distress (n = 87) experienced delayed feeding initiation, while time to resolution and hospital stay were similar.

Conclusion: Nitrogen washout is superior to targeted oxygen therapy in time to resolution in infants presenting with respiratory distress and desaturation.

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新生儿自发性气胸的结局：治疗vs.预期治疗

背景：新生儿气胸取决于症状的严重程度和泄漏的大小。氮气冲洗法治疗气胸存在争议。目的：比较新生儿自发性气胸（SP）治疗与预期治疗的结果。方法：回顾性分析2011年至2021年间出生的诊断为SP的新生儿（≥34周）的医疗记录。比较采用靶向氧疗（稳定饱和度≥93%）或氮洗脱治疗SP的新生儿和采用预期治疗的新生儿的新生儿特征和结局。结果：在呼吸窘迫和去饱和的新生儿中（n = 64），与靶向氧疗相比，氮洗脱可缩短中位缓解时间（31[12-67]对81[31.8-123.5]小时，p = 0.012）。预期处理的窘迫新生儿（n = 87）经历了延迟的喂养开始，而解决时间和住院时间相似。结论：氮洗脱法在解决新生儿呼吸窘迫和缺氧问题上优于靶向氧疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.