Homogeneous Dual-Mode ECL-FL Sensor for Sensitive Hydrogen Sulfide Detection: Mechanistic Insights and Applications in Environmental and Bioanalytical Monitoring

IF 12.2 1区环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL

Journal of Hazardous Materials Pub Date : 2025-03-16 DOI:10.1016/j.jhazmat.2025.137939

Binghui Li, Xin Wang, Xiaocui Yin, Huiting Hu, Guobing Wei, Jing Zhang, Hao Fan

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引用次数: 0

Abstract

A dual-mode electrochemiluminescence (ECL) and fluorescence (FL) probe was developed based on functionalized metal-organic framework nanosheets (RuMOFNSs) and (3-((2,4-dinitrophenyl)thio)phenyl)methanol (DNB) for the highly sensitive detection of hydrogen sulfide (H₂S) in homogeneous systems. Compared to conventional heterogeneous detection strategies, the homogeneous nature of this probe eliminates signal loss associated with solid-phase immobilization, thereby enhancing the interaction efficiency between the probe and target molecules. The developed sensing platform exhibited exceptional sensitivity, achieving detection limits of 0.18 pM in ECL and 0.4 nM in FL, with recovery rates ranging from 96.1% to 101.7%. Moreover, the probe demonstrated high selectivity against potential interfering metal ions and proved effective for monitoring food spoilage and dynamic H₂S fluctuations in rat brain tissue. Compared to existing detection approaches, this dual-mode probe offers superior sensitivity, selectivity, and broader applicability, underscoring its potential for environmental and biomedical analyse

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用于灵敏检测硫化氢的同质双模式 ECL-FL 传感器：环境和生物分析监测中的机理认识和应用

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来源期刊

Journal of Hazardous Materials 工程技术-工程：环境

CiteScore

25.40

自引率

5.90%

发文量

3059

审稿时长

58 days

期刊介绍： The Journal of Hazardous Materials serves as a global platform for promoting cutting-edge research in the field of Environmental Science and Engineering. Our publication features a wide range of articles, including full-length research papers, review articles, and perspectives, with the aim of enhancing our understanding of the dangers and risks associated with various materials concerning public health and the environment. It is important to note that the term "environmental contaminants" refers specifically to substances that pose hazardous effects through contamination, while excluding those that do not have such impacts on the environment or human health. Moreover, we emphasize the distinction between wastes and hazardous materials in order to provide further clarity on the scope of the journal. We have a keen interest in exploring specific compounds and microbial agents that have adverse effects on the environment.