Quality of life in patients with progressive keratoconus treated with corneal collagen crosslinking.

IF 1.4 4区医学 Q3 OPHTHALMOLOGY

International Ophthalmology Pub Date : 2025-03-14 DOI:10.1007/s10792-024-03400-6

J Steinberg, P Fischer, A Frings, V Druchkiv, T Katz, S J Linke

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引用次数: 0

Abstract

Purpose: This study aims to analyze the vision-related quality of life (vr-QoL) in keratoconus (KC) patients after corneal crosslinking (CXL).

Methods: A prospective clinical study was conducted, wherein 41 patients underwent assessment using the "National Eye Institute Visual Functioning Questionnaire" (NEI-25) and the "Keratoconus Outcomes Research Questionnaire" (KORQ) to evaluate vr-QoL, along with the examination of morphology and functional parameters before CXL, and at three and six months post-treatment. Rasch analyses were used to verify the measurement precision of the KORQ with our study population.

Results: There were no statistically significant changes observed in corneal morphology and best corrected visual acuity after CXL. Analysis of the NEI-25 questionnaires and KORQ demonstrated no statistically significant changes throughout the follow-up period. Rasch analyses revealed a high measurement precision of the KORQ within our population.

Conclusion: The study indicates that patients with progressive KC maintain stable vr-QoL after undergoing CXL. Based on our findings, we suggest considering very early CXL treatment for KC patients that are at high risk of progression.

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目的：本研究旨在分析角膜交联术（CXL）后角膜炎患者与视力相关的生活质量（vr-QoL）：41名患者接受了 "美国国家眼科研究所视觉功能问卷"（NEI-25）和 "角膜病结果研究问卷"（KORQ）的评估，以评价vr-QoL，并在CXL治疗前、治疗后3个月和6个月检查了形态和功能参数。我们使用拉氏分析法来验证 KORQ 在研究人群中的测量精度：结果：CXL 治疗后，角膜形态和最佳矫正视力均无统计学意义上的明显变化。对NEI-25调查问卷和KORQ的分析表明，在整个随访期间均无统计学意义上的显著变化。Rasch分析表明，在我们的研究人群中，KORQ的测量精度很高：研究表明，进行性 KC 患者在接受 CXL 治疗后，其生活质量仍能保持稳定。根据我们的研究结果，我们建议有进展风险的 KC 患者考虑尽早接受 CXL 治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Ophthalmology OPHTHALMOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

451

期刊介绍： International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.