Normal ranges of the fetal weight determined by ultrasound in the population of the Hospital das Clínicas of the Faculdade de Medicina da Universidade de São Paulo

IF 2.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Clinics Pub Date : 2025-01-01 DOI:10.1016/j.clinsp.2025.100616

Eliane Azeka Hase, Amanda Amaral, Stela Verzinhasse Peres, Rossana Pulcineli Vieira Francisco

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Abstract

Objective

This study aimed to determine the normal range of fetal weight by ultrasound in pregnant women followed at the Obstetric Clinic of the Hospital das Clínicas of the Faculty of Medicine, University of São Paulo.

Methods

This retrospective cohort study included singleton pregnant women without associated maternal diseases, at 15–41 weeks of gestation, who underwent their last ultrasound up to 7 days before birth. Fetal parameters analyzed for the normal range were biparietal diameter, femur length, head and abdominal circumference. 3rd, 10th, 50th, 90th, and 97th weight percentiles were determined for each gestational age. Newborns were classified by birth weight as Small (SGA), Appropriate (AGA), or Large (LGA) for gestational age.

Results

Among 837 women admitted without maternal diseases, 136 were included and 379 examinations performed at 15–41 weeks of gestation. Multiple linear regression models were generated to develop the normal range of fetal weight. Three equations were selected, and six normal ranges were created considering the total population and stratified by fetal sex. Weight estimates were calculated for the 3rd, 10th, 50th, 90th, and 97th percentiles for each gestational age. Among the 136 newborns, 107 (78.7 %) were classified as AGA, 23 (16.9 %) as SGA, and 6 (4.4 %) as LGA.

Conclusion

The normal range of the fetal weight determined by ultrasound in this population showed a good correlation with gestational age, enabling the fetal weight gain pattern evaluation. The equation based on four parameters, including days before birth, presented the lowest percentage error variation to estimate the normal range.

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圣保罗大学医学院das医院人口超声测定胎儿体重的正常范围

目的：本研究旨在通过超声确定圣保罗大学医学院Clínicas医院产科门诊孕妇胎儿体重的正常范围。方法本回顾性队列研究纳入了妊娠15-41周无相关母体疾病的单胎孕妇，她们在出生前7天前进行了最后一次超声检查。正常范围内的胎儿参数包括双顶骨直径、股骨长、头围和腹围。测定每个胎龄的第3、第10、第50、第90和第97个体重百分位数。新生儿按出生体重分为小（SGA），适当（AGA），或大（LGA）胎龄。结果837例无孕产妇疾病的住院妇女中，136例纳入，379例在妊娠15 ~ 41周检查。采用多元线性回归模型建立胎儿体重正常范围。选取3个方程，根据总体情况建立6个正常范围，并按胎儿性别分层。计算每个胎龄的第3、第10、第50、第90和第97百分位的体重估计值。136例新生儿中，AGA 107例（78.7%），SGA 23例（16.9%），LGA 6例（4.4%）。结论超声测得的胎儿体重正常范围与胎龄有较好的相关性，可用于胎儿增重模式的评价。该方程基于四个参数，包括出生前天数，呈现出最低百分比的误差变化，以估计正常范围。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinics 医学-医学：内科

CiteScore

4.10

自引率

3.70%

发文量

129

审稿时长

52 days

期刊介绍： CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in the medical sciences. CLINICS complies with the policies of funding agencies which request or require deposition of the published articles that they fund into publicly available databases. CLINICS supports the position of the International Committee of Medical Journal Editors (ICMJE) on trial registration.