Relationship between gait asymmetry and time since amputation in individuals with unilateral transfemoral amputation

IF 2.4 3区医学 Q3 BIOPHYSICS

Journal of biomechanics Pub Date : 2025-03-08 DOI:10.1016/j.jbiomech.2025.112622

Takeshi Hara , Genki Hisano , Toshiki Kobayashi , Hélène Pillet , Ryota Morishima , Yukihiko Mizuno , Hiroaki Hobara

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引用次数: 0

Abstract

Although time since amputation (TSAmp) is recognized as a primary factor influencing the walking ability of individuals with unilateral transfemoral amputation (uTFA), the specific effects of TSAmp on gait asymmetry remain insufficiently investigated. This study aimed to clarify whether gait asymmetry decrease with longer TSAmp across a range of walking speeds. Thirty individuals with uTFA, classified as K-3 and K-4 functional levels, participated in this study. Participants walked at eight speeds (ranging from 2.0 to 5.5 km/h in increments of 0.5 km/h) on an instrumented treadmill. Spatiotemporal parameters and peak values of ground reaction forces (GRFs), including anteroposterior, mediolateral, and vertical components, were measured to calculate the asymmetry ratio. Linear regression analyses were subsequently conducted to examine the relationships between TSAmp, TSAmp/Age (age-normalized TSAmp), and the asymmetry ratio. The results demonstrated no significant correlations between TSAmp, TSAmp/Age, and the asymmetry ratio across all measured parameters and walking speeds. These findings suggest that TSAmp and TSAmp/Age exhibit weak associations with gait asymmetry in terms of spatiotemporal parameters and peak GRFs. The results of the present study suggest that neither TSAmp nor TSAmp/Age are necessarily associated with gait asymmetry. Therefore, predicting gait asymmetry in individuals with uTFA based solely on TSAmp is not feasible.

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单侧经股截肢患者步态不对称与截肢后时间的关系

虽然截肢后时间（TSAmp）被认为是影响单侧经股截肢（uTFA）患者行走能力的主要因素，但TSAmp对步态不对称的具体影响仍未得到充分研究。这项研究的目的是澄清步态不对称性是否会随着TSAmp的增加而减少。30例uTFA患者参与了本研究，分为K-3和K-4功能水平。参与者在跑步机上以8种速度（从2.0到5.5公里/小时，每小时增加0.5公里/小时）行走。测量地面反作用力（GRFs）的时空参数和峰值，包括正向、中外侧和垂直分量，以计算不对称比。随后进行线性回归分析，检验TSAmp、TSAmp/Age（年龄归一化TSAmp）和不对称比之间的关系。结果表明，TSAmp、TSAmp/Age与所有测量参数和步行速度的不对称比之间没有显著相关性。这些结果表明，TSAmp和TSAmp/Age与步态不对称性在时空参数和峰值GRFs方面表现出较弱的相关性。本研究的结果表明，无论是TSAmp还是TSAmp/Age与步态不对称都没有必然的联系。因此，仅根据TSAmp预测uTFA患者的步态不对称性是不可实现的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of biomechanics 生物-工程：生物医学

CiteScore

5.10

自引率

4.20%

发文量

345

审稿时长

1 months

期刊介绍： The Journal of Biomechanics publishes reports of original and substantial findings using the principles of mechanics to explore biological problems. Analytical, as well as experimental papers may be submitted, and the journal accepts original articles, surveys and perspective articles (usually by Editorial invitation only), book reviews and letters to the Editor. The criteria for acceptance of manuscripts include excellence, novelty, significance, clarity, conciseness and interest to the readership. Papers published in the journal may cover a wide range of topics in biomechanics, including, but not limited to: -Fundamental Topics - Biomechanics of the musculoskeletal, cardiovascular, and respiratory systems, mechanics of hard and soft tissues, biofluid mechanics, mechanics of prostheses and implant-tissue interfaces, mechanics of cells. -Cardiovascular and Respiratory Biomechanics - Mechanics of blood-flow, air-flow, mechanics of the soft tissues, flow-tissue or flow-prosthesis interactions. -Cell Biomechanics - Biomechanic analyses of cells, membranes and sub-cellular structures; the relationship of the mechanical environment to cell and tissue response. -Dental Biomechanics - Design and analysis of dental tissues and prostheses, mechanics of chewing. -Functional Tissue Engineering - The role of biomechanical factors in engineered tissue replacements and regenerative medicine. -Injury Biomechanics - Mechanics of impact and trauma, dynamics of man-machine interaction. -Molecular Biomechanics - Mechanical analyses of biomolecules. -Orthopedic Biomechanics - Mechanics of fracture and fracture fixation, mechanics of implants and implant fixation, mechanics of bones and joints, wear of natural and artificial joints. -Rehabilitation Biomechanics - Analyses of gait, mechanics of prosthetics and orthotics. -Sports Biomechanics - Mechanical analyses of sports performance.