Aminoisothiazolamides, a new class of potent inhibitors of lysyl-tRNA synthetase

IF 3.8 1区农林科学 Q1 AGRONOMY

Pest Management Science Pub Date : 2025-03-14 DOI:10.1002/ps.8759

David Bernier, David M Barber, Guido Bojack, Birgit Bollenbach-Wahl, Luke Churchman, Uwe Döller, Tyler Fahrenhorst-Jones, Jörg Freigang, Elmar Gatzweiler, Claudia Hartfiel, Caroline Hilmi, Yoann Huet, Bernd Laber, Gudrun Lange, Stephanie Lee, Virginie Lempereur, Marc Mosrin, Thomas Müller, China M Payne, Olaf Peters, Luka Posa, Shaun Rees, Anna M Reingruber, Jullien Rey, Jörg Tiebes, Karen Tilmant, Jens Frackenpohl

引用次数: 0

Abstract

Owing to the economic relevance of resistance evolution against herbicides, new chemical entities addressing unprecedented molecular targets are urgently needed to develop future sustainable weed control solutions. As part of our discovery research, the new class of aminoisothiazolamides was investigated.

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氨基异噻唑胺，一类新的赖氨酸- trna合成酶有效抑制剂

由于对除草剂抗性进化的经济相关性，迫切需要新的化学实体来解决前所未有的分子目标，以开发未来可持续的杂草控制解决方案。作为我们发现研究的一部分，我们研究了一类新的氨基异噻唑胺。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pest Management Science 农林科学-昆虫学

CiteScore

7.90

自引率

9.80%

发文量

553

审稿时长

4.8 months

期刊介绍： Pest Management Science is the international journal of research and development in crop protection and pest control. Since its launch in 1970, the journal has become the premier forum for papers on the discovery, application, and impact on the environment of products and strategies designed for pest management. Published for SCI by John Wiley & Sons Ltd.