Neonatal Neurobehavior Predicts Neonatal Opioid Withdrawal Syndrome Severity Prior to Treatment Interventions.

IF 3.9 2区医学 Q1 PEDIATRICS

Journal of Pediatrics Pub Date : 2025-03-11 DOI:10.1016/j.jpeds.2025.114533

Sarah E Maylott, Madeleine Bruce, Lydia Brown, Ayla J Castano, Lynne Dansereau, Barry Lester, Elisabeth Conradt

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引用次数: 0

Abstract

Objective: To utilize the NeoNatal Neurobehavioral Scale (NNNS-II) as a standardized and reliable tool to help guide treatment of neonatal opioid withdrawal syndrome (NOWS) with the goal of improving the consistency and quality of care provided to opioid-exposed newborns.

Study design: We examined NOWS severity through several indicators, including the number of pharmacological treatment medications, maximum dose of medications, length of treatment, and maximum score on NOWS observational tools to create an overall severity score for each newborn. Then we examined whether NOWS risk could be detected as early as 24 hours after birth using the NNNS-II to predict NOWS severity.

Results: Newborn neurobehavior prior to signs of NOWS predicted NOWS severity. Newborns who were more hypertonic and had poorer quality of movement had higher severity scores.

Conclusion: These findings indicate that NOWS risk detection may be enhanced with an early newborn neurobehavioral assessment.

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来源期刊

Journal of Pediatrics 医学-小儿科

CiteScore

6.00

自引率

2.00%

发文量

696

审稿时长

31 days

期刊介绍： The Journal of Pediatrics is an international peer-reviewed journal that advances pediatric research and serves as a practical guide for pediatricians who manage health and diagnose and treat disorders in infants, children, and adolescents. The Journal publishes original work based on standards of excellence and expert review. The Journal seeks to publish high quality original articles that are immediately applicable to practice (basic science, translational research, evidence-based medicine), brief clinical and laboratory case reports, medical progress, expert commentary, grand rounds, insightful editorials, “classic” physical examinations, and novel insights into clinical and academic pediatric medicine related to every aspect of child health. Published monthly since 1932, The Journal of Pediatrics continues to promote the latest developments in pediatric medicine, child health, policy, and advocacy. Topics covered in The Journal of Pediatrics include, but are not limited to: General Pediatrics Pediatric Subspecialties Adolescent Medicine Allergy and Immunology Cardiology Critical Care Medicine Developmental-Behavioral Medicine Endocrinology Gastroenterology Hematology-Oncology Infectious Diseases Neonatal-Perinatal Medicine Nephrology Neurology Emergency Medicine Pulmonology Rheumatology Genetics Ethics Health Service Research Pediatric Hospitalist Medicine.