Efficacy of adjunctive injectable platelet-rich fibrin as a first-line treatment in temporomandibular joint osteoarthritis: a retrospective cohort study
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引用次数: 0
Abstract
This study was performed to compare the outcomes of adjunctive injections (injectable platelet-rich fibrin (iPRF), hyaluronic acid (HA)) and arthrocentesis only (AO) in the treatment of temporomandibular joint osteoarthritis. The study included 127 female patients (mean age 52.3 years). None of them had undergone prior occlusal splint therapy. The pain reduction (visual analogue scale) at 12 months post-treatment was the primary outcome variable, while maximum inter-incisal opening (MIO) at all follow-ups and pain at 1 and 6 months of follow-up were secondary outcome variables. All treatment groups showed significant improvements in pain and MIO at all postoperative follow-ups compared to baseline (P < 0.001). iPRF and HA resulted in significantly better pain relief than AO at all follow-ups (P < 0.01). There was no significant difference in pain alleviation between iPRF and HA. No differences were observed among the three groups in jaw mobility (MIO) at any follow-up. Since iPRF did not provide additional benefits over HA, the two treatments may be considered as alternatives, depending on cost considerations. Of note, the treatment objectives were achieved even without previous occlusal splint use.
期刊介绍:
The International Journal of Oral & Maxillofacial Surgery is one of the leading journals in oral and maxillofacial surgery in the world. The Journal publishes papers of the highest scientific merit and widest possible scope on work in oral and maxillofacial surgery and supporting specialties.
The Journal is divided into sections, ensuring every aspect of oral and maxillofacial surgery is covered fully through a range of invited review articles, leading clinical and research articles, technical notes, abstracts, case reports and others. The sections include:
• Congenital and craniofacial deformities
• Orthognathic Surgery/Aesthetic facial surgery
• Trauma
• TMJ disorders
• Head and neck oncology
• Reconstructive surgery
• Implantology/Dentoalveolar surgery
• Clinical Pathology
• Oral Medicine
• Research and emerging technologies.