{"title":"Visualization of Vestibular Aqueduct and Endolymphatic Hydrops in Meniere's Disease With 3D-Real IR.","authors":"Yan Huang, Qian Sun, Heyu Ding, Xu Han, Le Xia, Jicheng Wang, Zhenghan Yang, Shusheng Gong, Zhenchang Wang, Pengfei Zhao, Jing Xie","doi":"10.1002/lary.32122","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the association between the vestibular aqueduct (VA) and endolymphatic hydrops (EH) in patients with Meniere's disease (MD) using three-dimensional real inversion recovery (3D-real IR) sequences.</p><p><strong>Methods: </strong>This retrospective study included patients diagnosed with unilateral MD who underwent computed tomography (CT) and 3D-real IR sequencing. The VA course was identified on CT, and its visibility was assessed using a 3D-real IR sequence. The presence and severity of the cochlear and vestibular EH were evaluated. VA visualization was classified as Grade 0, whereas nonvisualization was classified as Grade 1. Differences in VA visibility between the affected and unaffected ears were compared, and correlations between VA visibility and EH severity were analyzed. Finally, the diagnostic efficacy of various MD indicators was assessed.</p><p><strong>Results: </strong>A total of 56 patients with unilateral MD were analyzed. The incidence rates of cochlear or vestibular EH were higher in the affected ear group than in the unaffected ear group (p < 0.001). The rates of nonvisualization of the VA in the affected and unaffected ears were 91.1% and 41.1%, respectively, with a statistically significant difference (χ<sup>2</sup> = 31.226, p < 0.001). The VA visualization status was positively correlated with vestibular and cochlear EH (p < 0.001). The area under the curve for diagnosing MD using combined VA nonvisualization and EH was 0.876, which was significantly higher than that obtained using EH alone (Z = 3.414, p = 0.001).</p><p><strong>Conclusion: </strong>VA visibility on 3D-real IR sequences may assist in the diagnosis of MD and associated EH.</p><p><strong>Level of evidence: 3: </strong></p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Laryngoscope","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/lary.32122","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: To investigate the association between the vestibular aqueduct (VA) and endolymphatic hydrops (EH) in patients with Meniere's disease (MD) using three-dimensional real inversion recovery (3D-real IR) sequences.
Methods: This retrospective study included patients diagnosed with unilateral MD who underwent computed tomography (CT) and 3D-real IR sequencing. The VA course was identified on CT, and its visibility was assessed using a 3D-real IR sequence. The presence and severity of the cochlear and vestibular EH were evaluated. VA visualization was classified as Grade 0, whereas nonvisualization was classified as Grade 1. Differences in VA visibility between the affected and unaffected ears were compared, and correlations between VA visibility and EH severity were analyzed. Finally, the diagnostic efficacy of various MD indicators was assessed.
Results: A total of 56 patients with unilateral MD were analyzed. The incidence rates of cochlear or vestibular EH were higher in the affected ear group than in the unaffected ear group (p < 0.001). The rates of nonvisualization of the VA in the affected and unaffected ears were 91.1% and 41.1%, respectively, with a statistically significant difference (χ2 = 31.226, p < 0.001). The VA visualization status was positively correlated with vestibular and cochlear EH (p < 0.001). The area under the curve for diagnosing MD using combined VA nonvisualization and EH was 0.876, which was significantly higher than that obtained using EH alone (Z = 3.414, p = 0.001).
Conclusion: VA visibility on 3D-real IR sequences may assist in the diagnosis of MD and associated EH.
期刊介绍：
The Laryngoscope has been the leading source of information on advances in the diagnosis and treatment of head and neck disorders since 1890. The Laryngoscope is the first choice among otolaryngologists for publication of their important findings and techniques. Each monthly issue of The Laryngoscope features peer-reviewed medical, clinical, and research contributions in general otolaryngology, allergy/rhinology, otology/neurotology, laryngology/bronchoesophagology, head and neck surgery, sleep medicine, pediatric otolaryngology, facial plastics and reconstructive surgery, oncology, and communicative disorders. Contributions include papers and posters presented at the Annual and Section Meetings of the Triological Society, as well as independent papers, "How I Do It", "Triological Best Practice" articles, and contemporary reviews. Theses authored by the Triological Society’s new Fellows as well as papers presented at meetings of the American Laryngological Association are published in The Laryngoscope.
• Broncho-esophagology
• Communicative disorders
• Head and neck surgery
• Plastic and reconstructive facial surgery
• Oncology
• Speech and hearing defects
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