Effect of Open Flap Debridement with and without LLLT in Patients with Periodontitis on Wound Healing, GCF ALP Levels, and Clinical Parameters.

Q3 Dentistry
Ritika Gupta, Sachit A Arora, Gunjan Gupta, Rupali Kalsi, Kumar Saurav, Shivesh K Mishra, Simran Saluja, Srishti Wadhwa
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引用次数: 0

Abstract

Aim: The tenet of the study is to evaluate the efficacy of low-level laser therapy (LLLT) as an adjunct to surgical periodontal therapy [open flap debridement (OFD)] on clinical parameters, gingival crevicular fluid (GCF) alkaline phosphatase (ALP) levels in GCF and wound healing.

Materials and methods: Thirty subjects afflicted with chronic periodontitis showing evidence of horizontal bone loss on the radiograph, pocket probing depth (PPD) between 4 and 7 mm, and ≥20 natural teeth present in the oral cavity were included in the study. In every patient, OFD+LLLT was done in one quadrant and OFD in another was performed. The clinical parameters were assessed at baseline, 3 and 6 months visits while the GCF sample was collected at baseline visit and 6 months recall. Wound healing indices were recorded 1-week post-op surgery for each group.

Results: The results showed an evident improvement in all the clinical parameters [pocket probing depth, gingival index (GI), plaque index (PI), and CAL] from baseline-6 months values; however, no statistically significant difference was seen on the intergroup comparison. Wound healing was statistically significantly superior in the OFD + LLLT group in comparison to the OFD group, indicating a positive effect of lasers on healing. Gingival crevicular fluid ALP levels in the two groups decreased after 6 months and a statistically significant reduction in the laser group indicated an anti-inflammatory effect.

Conclusion: The results clearly indicated the efficacy of lasers in terms of acceleration of wound healing and control of inflammation.

Clinical significance: Lasers as an adjunct to surgical periodontal therapy evidently have an anti-inflammatory effect (decrease in GCF ALP levels) as well as accelerate the wound healing process. How to cite this article: Gupta R, Arora SA, Gupta G, et al. Effect of Open Flap Debridement with and without LLLT in Patients with Periodontitis on Wound Healing, GCF ALP Levels, and Clinical Parameters. J Contemp Dent Pract 2024;25(12):1148-1155.

牙周炎患者带和不带LLLT的开放式皮瓣清创对伤口愈合、GCF ALP水平和临床参数的影响。
目的:本研究的目的是评估低水平激光治疗(LLLT)作为外科牙周治疗[开放式皮瓣清创(OFD)]的辅助治疗对临床参数、龈沟液(GCF)碱性磷酸酶(ALP)水平和伤口愈合的影响。材料和方法:30例慢性牙周炎患者在x线片上表现为水平骨丢失,口袋探测深度(PPD)在4 ~ 7 mm之间,口腔内存在≥20颗天然牙。每个患者在一个象限做OFD+LLLT,在另一个象限做OFD。在基线、3个月和6个月就诊时评估临床参数,同时在基线就诊和6个月回忆时收集GCF样本。记录各组术后1周创面愈合指标。结果:结果显示,所有临床参数[口袋探测深度,牙龈指数(GI),菌斑指数(PI)和CAL]较基线-6个月值有明显改善;但组间比较差异无统计学意义。与OFD组相比,OFD + LLLT组的伤口愈合在统计学上显著优于OFD组,表明激光对愈合有积极作用。6个月后,两组龈沟液ALP水平均下降,激光组有统计学意义的显著降低,表明具有抗炎作用。结论:激光治疗具有促进创面愈合和控制炎症的作用。临床意义:激光作为牙周外科治疗的辅助手段具有明显的抗炎作用(降低GCF ALP水平),并加速伤口愈合过程。本文引用方式:Gupta R, Arora SA, Gupta G,等。牙周炎患者带和不带LLLT的开放式皮瓣清创对伤口愈合、GCF ALP水平和临床参数的影响。[J]现代医学学报;2009;25(12):1148-1155。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Contemporary Dental Practice
Journal of Contemporary Dental Practice Dentistry-Dentistry (all)
CiteScore
1.80
自引率
0.00%
发文量
174
期刊介绍: The Journal of Contemporary Dental Practice (JCDP), is a peer-reviewed, open access MEDLINE indexed journal. The journal’s full text is available online at http://www.thejcdp.com. The journal allows free access (open access) to its contents. Articles with clinical relevance will be given preference for publication. The Journal publishes original research papers, review articles, rare and novel case reports, and clinical techniques. Manuscripts are invited from all specialties of dentistry i.e., conservative dentistry and endodontics, dentofacial orthopedics and orthodontics, oral medicine and radiology, oral pathology, oral surgery, orodental diseases, pediatric dentistry, implantology, periodontics, clinical aspects of public health dentistry, and prosthodontics.
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