The effect of extent and localization of precordial ST-segment depression in acute inferior myocardial infarction as an indicator of infarct severity, coronary artery involvement, and cardiac outcomes.
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引用次数: 0
Abstract
Background: It is crucial to timely recognize individuals presenting high-risk characteristics indicative of acute myocardial infarction.
Objectives: Our study aimed to analyze the significance of evaluating ST-segment depression in patients with acute inferior myocardial infarction (MI). We assessed precordial ST-T changes as an indicator of ongoing ischemia, examined their correlation with the extent of coronary artery involvement, and potential association with both early and late cardiac outcomes.
Methods: We enrolled 200 hospitalized patients with acute inferior MI who displayed ST depression in their precordial leads and underwent angiography. Individuals were divided into three groups based on the location of ST depression (V1-V3, V4-V6, and V1-V6). Demographic and echocardiographic data were extracted, and cardiac outcomes were assessed during hospitalization and follow-ups.
Results: The findings revealed significant associations between ST depression in leads V1-V6 and V4-V6 with left ventricular systolic dysfunction, mitral regurgitation severity, and the extent of coronary artery stenosis in comparison with ST depression in V1-V3 (p < 0.05). Furthermore, a notable connection was found between the involved vessels and the degree of ST depression in precordial leads (p < 0.05). Moreover, individuals with prominent ST depression in V1-V6 and V1-V3 exhibited poorer outcomes (p < 0.05).
Conclusion: Greater ST-segment depression in V1-V6 and V4-V6 in comparison with V1-V3 may signal multivessel disease, severe ischemia. Adverse outcomes like heart failure showed in V1-V6 especially V1-V3 versus V4-V6. This ST depression in acute inferior MI patients could indicate simultaneous ischemia or necrosis in other left ventricle regions, worsening cardiac function and prognosis. Thus, timely interventions are crucial.
急性下壁心肌梗死心前区 ST 段压低的范围和定位作为梗死严重程度、冠状动脉受累情况和心脏预后指标的影响。
背景：及时识别具有急性心肌梗死高危特征的个体是至关重要的。目的：分析评价急性下壁心肌梗死（MI）患者st段抑郁的意义。我们评估了心前ST-T变化作为持续缺血的指标，检查了它们与冠状动脉受累程度的相关性，以及与早期和晚期心脏结局的潜在关联。方法：我们招募了200例急性下段心肌梗死住院患者，他们在心前导联中表现出ST段抑制，并进行了血管造影。根据ST段凹陷位置将个体分为三组（V1-V3、V4-V6和V1-V6）。提取人口统计学和超声心动图数据，并在住院和随访期间评估心脏预后。结果：V1-V6和V4-V6导联ST段下降与左室收缩功能障碍、二尖瓣反流严重程度和冠状动脉狭窄程度有显著相关性（p p p）。结论：V1-V6和V4-V6导联ST段下降较V1-V3明显，可能预示着多血管疾病、严重缺血。心脏衰竭等不良反应在V1-V6尤其是V1-V3阶段与V4-V6阶段比较明显。急性下壁心肌梗死患者ST段下降可能提示左心室其他区域同时缺血或坏死，心功能恶化，影响预后。因此，及时干预至关重要。
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The journal is aimed at clinicians and researchers from the cardiovascular disease field and will be a forum for all views and reviews relating to this discipline.Topics covered will include: ·arteriosclerosis ·cardiomyopathies ·coronary artery disease ·diabetes ·heart failure ·hypertension ·metabolic syndrome ·obesity ·peripheral arterial disease ·stroke ·arrhythmias ·genetics
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