Tara C Klinedinst, Nicholas Hollman, Michael J Hankes, Raymond Jones
{"title":"Linking Social Cohesion to Biological Markers of Aging: Evidence From the National Health and Aging Trends Study.","authors":"Tara C Klinedinst, Nicholas Hollman, Michael J Hankes, Raymond Jones","doi":"10.1177/07334648251325623","DOIUrl":null,"url":null,"abstract":"<p><p>Social cohesion, a measure of community belonging, and inflammatory biomarkers, like interleukin-6 (IL-6) and c-reactive protein (CRP), have emerged as significant factors influencing age-related chronic conditions and functional decline among older adults. Understanding the link between social cohesion and inflammation is particularly relevant in aging populations, as with age, social networks often diminish, and the prevalence of inflammatory conditions increases. Using data from the National Health and Aging Trends Study (NHATS), we assessed the relationship between low social cohesion and IL-6 and CRP. We found that low social cohesion was associated with higher levels of CRP and IL-6 after adjusting for the influence of sociodemographic variables. These findings could inform health policies and community-level interventions designed to enhance social cohesion for aging adults.</p>","PeriodicalId":47970,"journal":{"name":"Journal of Applied Gerontology","volume":" ","pages":"7334648251325623"},"PeriodicalIF":2.2000,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Gerontology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/07334648251325623","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GERONTOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Social cohesion, a measure of community belonging, and inflammatory biomarkers, like interleukin-6 (IL-6) and c-reactive protein (CRP), have emerged as significant factors influencing age-related chronic conditions and functional decline among older adults. Understanding the link between social cohesion and inflammation is particularly relevant in aging populations, as with age, social networks often diminish, and the prevalence of inflammatory conditions increases. Using data from the National Health and Aging Trends Study (NHATS), we assessed the relationship between low social cohesion and IL-6 and CRP. We found that low social cohesion was associated with higher levels of CRP and IL-6 after adjusting for the influence of sociodemographic variables. These findings could inform health policies and community-level interventions designed to enhance social cohesion for aging adults.
期刊介绍:
The Journal of Applied Gerontology (JAG) is the official journal of the Southern Gerontological Society. It features articles that focus on research applications intended to improve the quality of life of older persons or to enhance our understanding of age-related issues that will eventually lead to such outcomes. We construe application broadly and encourage contributions across a range of applications toward those foci, including interventions, methodology, policy, and theory. Manuscripts from all disciplines represented in gerontology are welcome. Because the circulation and intended audience of JAG is global, contributions from international authors are encouraged.