Melano-erythrodermic folliculotropic mycosis fungoides misdiagnosed as a case of recalcitrant atopic dermatitis: A case report.

Abstract

Mycosis fungoides is the most common cutaneous T-cell lymphoma, with its folliculotropic variant being more aggressive and often misdiagnosed. We present a case of a 38-year-old woman initially diagnosed with severe atopic dermatitis, who later experienced generalized itching, hyperpigmentation, alopecia, and palmoplantar keratoderma over several years. A skin biopsy revealed atypical lymphocytic infiltration with folliculotropism, confirming the diagnosis of folliculotropic mycosis fungoides. This case underscores the diagnostic challenges of this condition, which shares features with common dermatological disorders, leading to delayed diagnosis and worse prognosis. Early detection is crucial for improved treatment outcomes.