A 128-channel receive array with enhanced signal-to-noise ratio performance for 10.5T brain imaging.

Abstract

Purpose: To develop and characterize a 128-channel head array for brain imaging at 10.5 T, evaluate signal-to-noise ratio (SNR) relative to ultimate intrinsic SNR (uiSNR) and lower field strengths, and demonstrate human brain anatomical and functional imaging with this unique magnetic field and high-channel-count array.

Methods: The coil consists of a 16-channel self-decoupled loop transmit/receive (16Tx/Rx) array with a 112-loop receive-only (Rx) insert. Interactions between the 16Tx/Rx array and the 112Rx insert were mitigated using coaxial cable traps placed every 1/16 of a wavelength on each feed cable, locating most preamplifier boards outside the transmitter field, and miniaturizing those placed directly on individual coils.

Results: The effect of the 112Rx insert on the circumscribing 16Tx/Rx array was minimized, leading to similar transmit field maps obtained experimentally with and without the 112Rx array in place and by electromagnetic simulations of the 16Tx/Rx array alone. The 128-channel array captured 77% of uiSNR centrally. Significantly higher 1/g-factor values across the whole brain was achieved compared with 7 T. Excellent SNR, high parallel-imaging performance, and minimal Tx-Rx interactions collectively facilitated acquisition of high-quality, high-resolution, proof-of-concept functional and anatomical images, including with power-demanding sequences in the human brain.

Conclusions: Counterintuitive to expectations based on magnetic fields less than or equal to 7 T, the higher channel counts provided SNR gains centrally, capturing about 80% uiSNR. The fraction of uiSNR achieved centrally in 64Rx, 80Rx, and 128Rx arrays suggested that a plateau was being reached at 80%. At this plateau, B₀-dependent SNR gains for 10.5 T relative to 7 T were approximately linear to quadratic for the periphery and the center, respectively.