A 128-channel receive array with enhanced signal-to-noise ratio performance for 10.5T brain imaging

IF 3 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Magnetic Resonance in Medicine Pub Date : 2025-03-13 DOI:10.1002/mrm.30476

Russell L. Lagore, Alireza Sadeghi-Tarakameh, Andrea Grant, Matt Waks, Edward Auerbach, Steve Jungst, Lance DelaBarre, Steen Moeller, Yigitcan Eryaman, Riccardo Lattanzi, Ilias Giannakopoulos, Luca Vizioli, Essa Yacoub, Simon Schmidt, Gregory J. Metzger, Xiaoping Wu, Gregor Adriany, Kamil Uğurbil

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引用次数: 0

Abstract

Purpose

To develop and characterize a 128-channel head array for brain imaging at 10.5 T, evaluate signal-to-noise ratio (SNR) relative to ultimate intrinsic SNR (uiSNR) and lower field strengths, and demonstrate human brain anatomical and functional imaging with this unique magnetic field and high-channel-count array.

Methods

The coil consists of a 16-channel self-decoupled loop transmit/receive (16Tx/Rx) array with a 112-loop receive-only (Rx) insert. Interactions between the 16Tx/Rx array and the 112Rx insert were mitigated using coaxial cable traps placed every 1/16 of a wavelength on each feed cable, locating most preamplifier boards outside the transmitter field, and miniaturizing those placed directly on individual coils.

Results

The effect of the 112Rx insert on the circumscribing 16Tx/Rx array was minimized, leading to similar transmit field maps obtained experimentally with and without the 112Rx array in place and by electromagnetic simulations of the 16Tx/Rx array alone. The 128-channel array captured 77% of uiSNR centrally. Significantly higher 1/g-factor values across the whole brain was achieved compared with 7 T. Excellent SNR, high parallel-imaging performance, and minimal Tx-Rx interactions collectively facilitated acquisition of high-quality, high-resolution, proof-of-concept functional and anatomical images, including with power-demanding sequences in the human brain.

Conclusions

Counterintuitive to expectations based on magnetic fields less than or equal to 7 T, the higher channel counts provided SNR gains centrally, capturing about 80% uiSNR. The fraction of uiSNR achieved centrally in 64Rx, 80Rx, and 128Rx arrays suggested that a plateau was being reached at 80%. At this plateau, B₀-dependent SNR gains for 10.5 T relative to 7 T were approximately linear to quadratic for the periphery and the center, respectively.

Abstract Image

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一种具有增强信噪比的128通道接收阵列，用于10.5T脑成像。

目的：开发和表征用于10.5 T脑成像的128通道头部阵列，评估相对于最终固有信噪比（usisnr）和较低场强的信噪比（SNR），并展示该独特磁场和高通道计数阵列的人脑解剖和功能成像。方法：线圈由一个16通道自解耦环路发射/接收（16Tx/Rx）阵列和一个112环路仅接收（Rx）插入组成。通过同轴电缆陷阱，16Tx/Rx阵列和112Rx插入之间的相互作用得到了缓解，这些陷阱在每根馈电电缆上每隔1/16个波长放置一次，将大多数前置放大器板放置在发射机场之外，并将直接放置在单个线圈上的陷阱缩小。结果：112Rx插入对周边16Tx/Rx阵列的影响被最小化，导致在有和没有112Rx阵列的情况下，以及通过单独的16Tx/Rx阵列的电磁模拟得到相似的发射场图。128通道阵列集中捕获77%的usisnr。与7 T相比，整个大脑的1/g因子值明显更高。出色的信噪比、高并行成像性能和最小的Tx-Rx相互作用共同促进了高质量、高分辨率、概念验证功能和解剖图像的获取，包括人脑中功率要求高的序列。结论：与基于小于或等于7 T磁场的预期相反，较高的通道数集中提供了信噪比增益，捕获了约80%的用户信噪比。在64Rx、80Rx和128Rx阵列中集中实现的usisnr比例表明，在80%处达到了平稳期。在这个平台上，相对于7 T， b0相关的信噪比增益在外围和中心分别近似为线性到二次。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Magnetic Resonance in Medicine 医学-核医学

CiteScore

6.70

自引率

24.20%

发文量

376

审稿时长

2-4 weeks

期刊介绍： Magnetic Resonance in Medicine (Magn Reson Med) is an international journal devoted to the publication of original investigations concerned with all aspects of the development and use of nuclear magnetic resonance and electron paramagnetic resonance techniques for medical applications. Reports of original investigations in the areas of mathematics, computing, engineering, physics, biophysics, chemistry, biochemistry, and physiology directly relevant to magnetic resonance will be accepted, as well as methodology-oriented clinical studies.