Nguyen Van Hop, Nguyen Le My Linh, Vo Chau Ngoc Anh, Do Mai Nguyen, Tran Thanh Tam Toan
{"title":"Fe<sub>2</sub>O<sub>3</sub>-rice straw carbon dot composite for simultaneous electrochemical detection of dopamine and salbutamol.","authors":"Nguyen Van Hop, Nguyen Le My Linh, Vo Chau Ngoc Anh, Do Mai Nguyen, Tran Thanh Tam Toan","doi":"10.1039/d5na00065c","DOIUrl":null,"url":null,"abstract":"<p><p>A novel electrochemical sensor was developed using a composite of iron oxide (Fe<sub>2</sub>O<sub>3</sub>) and rice straw-based carbon dots (RSCD) for the simultaneous detection of dopamine (DPM) and salbutamol (SBT). By modifying a glassy carbon electrode (GCE) with the synthesized composite, the sensor achieved detection limits of 0.02 μM for DPM and 0.03 μM for SBT, with a linear range extending from 0.1 to 92 μM. Differential pulse voltammetry (DPV) demonstrated the sensor's enhanced sensitivity, selectivity, and resolution of overlapping oxidation peaks, overcoming key limitations of existing methods. Practical applications in neurotransmitter monitoring and food safety were validated using actual samples, highlighting the sensor's accuracy and reliability. This study introduces a scalable and cost-effective solution for electrochemical sensing with significant potential for broader societal impact.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6000,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11897740/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanoscale Advances","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1039/d5na00065c","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A novel electrochemical sensor was developed using a composite of iron oxide (Fe2O3) and rice straw-based carbon dots (RSCD) for the simultaneous detection of dopamine (DPM) and salbutamol (SBT). By modifying a glassy carbon electrode (GCE) with the synthesized composite, the sensor achieved detection limits of 0.02 μM for DPM and 0.03 μM for SBT, with a linear range extending from 0.1 to 92 μM. Differential pulse voltammetry (DPV) demonstrated the sensor's enhanced sensitivity, selectivity, and resolution of overlapping oxidation peaks, overcoming key limitations of existing methods. Practical applications in neurotransmitter monitoring and food safety were validated using actual samples, highlighting the sensor's accuracy and reliability. This study introduces a scalable and cost-effective solution for electrochemical sensing with significant potential for broader societal impact.