Significant initial hyperglycemia in young children with intracranial hemorrhage related to abuse.

IF 1.5 4区 医学 Q4 NEUROSCIENCES
Melanie M Randall, Christine L S Lee, Colleen Walsh Lang, Luke R Sampson, Brian G Chen, Lance A Brown
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引用次数: 0

Abstract

Introduction: Abusive head injury is more common in younger children, with long lasting physical or neurologic impairments seen in many survivors. There is a close relationship between hyperglycemia and head injury, with hyperglycemia associated with worse outcomes. Our hypothesis is that abusive head injury patients are more likely to have significant hyperglycemia.

Methods: This study is a retrospective review of pediatric emergency department patients less than three years with traumatic intracranial hemorrhage. Demographics, laboratory values, and imaging results were recorded.

Results: In total, 179 patients were analyzed. The median initial glucose for abuse patients was 164 mg/dL. The median initial glucose for non-abuse patients was 99 mg/dL. Eight patients had glucose levels greater than 300 mg/dL. All of these patients were abuse victims. The initial glucose level was significant for the diagnosis of child abuse, ICU admission, need for neurosurgical intervention, and mortality.

Discussion: Young children with intracranial hemorrhage and initial glucose levels greater than 300 mg/dL were all found to be abuse victims. A very high initial glucose can prompt a provider to evaluate for abusive head injury. In cases of a sick infant with glucose greater than 300 mg/dl, the consideration of abuse should play a prominent role in the differential.

与虐待相关的颅内出血的幼儿显著的初始高血糖。
虐待性头部损伤在年幼的儿童中更为常见,在许多幸存者中可以看到持久的身体或神经损伤。高血糖与头部损伤密切相关,高血糖与较差的预后相关。我们的假设是,虐待性头部损伤患者更有可能出现明显的高血糖症。方法:回顾性分析儿科急诊科3年以内外伤性颅内出血患者的临床资料。记录人口统计学、实验室值和影像学结果。结果:共分析179例患者。滥用患者的初始血糖中位数为164 mg/dL。非滥用患者的初始血糖中位数为99 mg/dL。8名患者的血糖水平高于300 mg/dL。这些病人都是虐待的受害者。初始血糖水平对儿童虐待、ICU入院、神经外科干预和死亡率的诊断具有重要意义。讨论:颅内出血和初始血糖水平大于300 mg/dL的幼儿都被认为是虐待受害者。一个非常高的初始葡萄糖可以提示提供者评估虐待性头部损伤。在患病婴儿血糖高于300 mg/dl的情况下,滥用的考虑应在鉴别中发挥突出作用。
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来源期刊
Brain injury
Brain injury 医学-康复医学
CiteScore
3.50
自引率
5.30%
发文量
148
审稿时长
12 months
期刊介绍: Brain Injury publishes critical information relating to research and clinical practice, adult and pediatric populations. The journal covers a full range of relevant topics relating to clinical, translational, and basic science research. Manuscripts address emergency and acute medical care, acute and post-acute rehabilitation, family and vocational issues, and long-term supports. Coverage includes assessment and interventions for functional, communication, neurological and psychological disorders.
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