A randomized controlled trial comparing liquid skin adhesives and staplers for surgical wound management.

IF 1.6 4区医学 Q3 SURGERY

Annals of Surgical Treatment and Research Pub Date : 2025-03-01 Epub Date: 2025-02-28 DOI:10.4174/astr.2025.108.3.143

Hyeon Woo Bae, Seung Yoon Yang, Ga Yoon Ku, Sohye Lee, Eun-Joo Jung, Seulkee Park, Yoon Bin Jung, Jihong Kim, Byung Soh Min

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引用次数: 0

Abstract

Purpose: Despite the widespread use of liquid skin adhesives (LSA), concerns persist regarding the increase in wound care costs. This study aimed to investigate the cost-effectiveness of LSA for surgical wound management.

Methods: In this prospective, open-label, single-center randomized controlled trial, adults aged 19 years and older who were scheduled for elective minimally invasive colorectal surgeries were included. The participants were randomly divided into 2 groups: an n-butyl cyanoacrylate skin adhesive was used in the experimental group (LSA group), while a surgical skin stapler was employed in the control group (stapler group). The primary outcome measure was the sum of the total time required for wound management.

Results: A total of 58 patients were randomly assigned to 2 groups, with 29 patients in each group. The findings revealed comparable wound complication rates in the 2 groups (8 out of 29 in the LSA group vs. 5 out of 29 in the stapler group, P = 0.530). Notably, the LSA group had a significantly shorter wound management time (median 235 seconds vs. 1,201 seconds, P < 0.001) and similar wound management cost (median US dollar [USD] 50.6 vs. USD 54.6, P = 0.529) compared to the stapler group. Subgroup analysis showed that the LSA group had a shorter management time for uncomplicated wounds and a lower cost for complicated wounds.

Conclusion: LSA not only provides a safe alternative but also offers a resource-efficient option for wound management compared to staplers.

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一项比较液体皮肤粘接剂和吻合器用于外科伤口处理的随机对照试验。

目的：尽管液体皮肤粘接剂（LSA）的广泛使用，但对伤口护理费用增加的担忧仍然存在。本研究旨在探讨LSA在外科伤口处理中的成本-效果。方法：在这项前瞻性、开放标签、单中心随机对照试验中，纳入了19岁及以上计划进行选择性微创结直肠手术的成年人。随机分为两组：实验组采用氰基丙烯酸酯正丁酯皮肤胶粘剂（LSA组），对照组采用外科皮肤吻合器（吻合器组）。主要结局指标是伤口处理所需总时间的总和。结果：58例患者随机分为2组，每组29例。结果显示两组的伤口并发症发生率相当（LSA组29例中有8例，吻合器组29例中有5例，P = 0.530）。值得注意的是，与订书机组相比，LSA组的伤口管理时间明显更短（中位235秒vs. 1201秒，P < 0.001），伤口管理成本相似（中位美元[USD] 50.6 vs. 54.6美元，P = 0.529）。亚组分析显示，LSA组对非复杂伤口的治疗时间较短，对复杂伤口的治疗费用较低。结论：与吻合器相比，LSA不仅提供了一种安全的选择，而且提供了一种资源有效的伤口管理选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Surgical Treatment and Research SURGERY-

CiteScore

2.30

自引率

7.10%

发文量

期刊介绍： Manuscripts to the Annals of Surgical Treatment and Research (Ann Surg Treat Res) should be written in English according to the instructions for authors. If the details are not described below, the style should follow the Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writing and Editing for Biomedical Publications available at International Committee of Medical Journal Editors (ICMJE) website (http://www.icmje.org).