Intramolecular Halogen Bonds Assist in Activating Carbonyl Groups for the Catalytic Synthesis of Bis(indolyl)methanes.

IF 3.5 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - An Asian Journal Pub Date : 2025-03-14 DOI:10.1002/asia.202401545

Jian-Wei Han, Yingying Hou, Lin Zhu, Taiyou Liu, Limin Wang, Ruimin Wang, Ulli Englert

引用次数: 0

Abstract

Ortho-carboxyl-substitution increases the acidity of hypervalent diaryliodonium salts and makes them useful catalysts in the synthesis of bis(indolyl)methanes under mild conditions, with yields up to 98%. The halogen bond-assisted hydrogen bonding was demonstrated by crystal structure analysis. The interaction distance of 2.619 Å between I(III) and the carboxyl O atom indicates either a long covalent or a very short halogen bond; analysis of the electron density shows the latter description is appropriate.

查看原文本刊更多论文

分子内卤素键有助于活化双(吲哚基)甲烷催化合成中的羰基。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Chemistry - An Asian Journal 化学-化学综合

CiteScore

7.00

自引率

2.40%

发文量

535

审稿时长

1.3 months

期刊介绍： Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).