Photocatalytic Cascade Alkylation/Cyclization of N‐Arylacrylamides with Simple Alkanes: A Convenient Approach to Quaternary C3 Alkylated Oxindoles

IF 2.8 4区化学 Q1 CHEMISTRY, ORGANIC

Asian Journal of Organic Chemistry Pub Date : 2025-03-01 DOI:10.1002/ajoc.202400554

Liang Ye , Haibin Xu , Jiong Yu , Han Yan , Min Wang , Pinhua Li

引用次数: 0

Abstract

A convenient and efficient protocol for the synthesis of 3,3‐dialkylated oxindoles through photocatalytic aerobic radical‐cascade alkylation/cyclization of N‐arylacrylamides with the alkyl radicals generated from simple alkanes is described. This method features a broad substrate scope, inexpensive alkyl radical precursors, simple conditions and good yields.

查看原文本刊更多论文

n -芳基丙烯酰胺与简单烷烃的光催化级联烷基化/环化：一种制备季3烷基化氧吲哚的便捷方法

介绍了一种简单烷烃生成的烷基自由基光催化n -芳基丙烯酰胺的好氧自由基级联烷基化/环化合成3,3-二烷基化氧吲哚的简便高效方法。该方法具有底物范围广、烷基自由基前体物价格低廉、条件简单、产率高等特点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.