Oj Shikhar Srivastava , Ruchir Kant , Dr. Namrata Rastogi
{"title":"Photocatalytic Csp2−H Amination of Hydrazones with N‐aminopyridinium Salts","authors":"Oj Shikhar Srivastava , Ruchir Kant , Dr. Namrata Rastogi","doi":"10.1002/ajoc.202400757","DOIUrl":null,"url":null,"abstract":"<div><div>The current approach describes Csp<sup>2</sup>−H amination of aldehyde‐derived hydrazones via nitrogen centred radical generation from <em>N‐</em>aminopyridinium salts under photocatalytic conditions. The scope of reaction is wide in terms of both the substrates and most of the products were isolated in good yields furnishing <em>Z</em>‐isomer exclusively. Further, aminated hydrazones were hydrolyzed to give amides resulting into indirect Csp<sup>2</sup>−H amination of aldehydes.</div></div>","PeriodicalId":130,"journal":{"name":"Asian Journal of Organic Chemistry","volume":"14 3","pages":"Article e202400757"},"PeriodicalIF":2.8000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S2193580725000406","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
The current approach describes Csp2−H amination of aldehyde‐derived hydrazones via nitrogen centred radical generation from N‐aminopyridinium salts under photocatalytic conditions. The scope of reaction is wide in terms of both the substrates and most of the products were isolated in good yields furnishing Z‐isomer exclusively. Further, aminated hydrazones were hydrolyzed to give amides resulting into indirect Csp2−H amination of aldehydes.
期刊介绍:
Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC)
The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.