Adenoid ameloblastoma with dentinoid: a case report

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.071

Eduardo dos Santos Vidal, William Cezar da Silveira, Hélen Kaline Farias Bezerra, Camila Cerantula Moura, Leandro Eduardo Klüppel, Pablo Agustin Vargas, Heliton Gustavo de Lima

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Abstract

A 32-year-old Caucasian female presented with a friable, hemorrhagic intraoral nodule associated with impacted tooth 48, exhibiting a roseus coloration, soft consistency, and a sessile with a 2 cm extension, evolving over a 3-year period. Cone-beam computed tomography revealed intraosseous evidence of a hypodense region associated with tooth 48. In the axial section, bone cortex expansion and buccal/lingual fenestrations were noted. Initial diagnostic considerations included dentigerous cyst and ameloblastoma. An incisional biopsy confirmed the diagnosis as conventional ameloblastoma with an acanthomatous pattern. Following complete lesion removal, microscopic analysis revealed, in addition to the ameloblastoma component, duct-like structures, a cribriform architecture, and the presence of dentinoid material, supported by positive immunohistochemical stains (CK19, CK14, β-catenin) and low Ki-67 (<5%), confirming adenoid ameloblastoma with dentinoid. While studies have documented cases of this new entity in the gnathic bones, further characterization is crucial for understanding its etiopathogenesis and biological behavior.

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.