A mass in the tongue of an 11-month-old baby

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.011

Isadora Pereira Gomes, Nathalia Rodrigues Gomes, Henrique Bemfica de Freitas Faria, Renata Gonçalves de Resende, Júlio César Tanos de Lacerda, Ricardo Alves de Mesquita, Ricardo Santiago Gomez

引用次数: 0

Abstract

An 11-month-old baby presented at the stomatology service with a tumor growth located in the tongue dorsum, which had been evolving for 10 months. Suspecting a congenital malformation, the lesion was surgically excised and sent for histopathological analysis. Microscopic examination revealed a mass characterized by the proliferation of mature neuroglial tissue interwoven with a homogeneous eosinophilic stroma, extending deeply into the tongue muscle. Many astrocytes, microglial cells, and oligodendrocytes were present. Immunohistochemical staining for GFAP, S-100, and vimentin showed strong positivity, while AML was also positive, and the ki67 proliferation index was <1% in the neuroglial tissue. With these findings, the final diagnosis was of glial choristoma.

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一个11个月大的婴儿舌头上的肿块

一名11个月大的婴儿因舌背肿瘤生长而就诊，该肿瘤已经发展了10个月。怀疑是先天性畸形，手术切除病变并送去组织病理分析。镜下检查发现一个肿块，其特征是成熟神经胶质组织的增生与均匀的嗜酸性间质交织在一起，深入舌肌。可见星形胶质细胞、小胶质细胞和少突胶质细胞。免疫组化染色GFAP、S-100、vimentin呈强阳性，AML也呈阳性，神经胶质组织中ki67增殖指数为1%。根据这些结果，最终诊断为神经胶质瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.