Oral low-grade fibromyxoid sarcoma: a case report

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.007

Cleiton Rone dos Santos Lima, Victor Hugo Lopes de Oliveira Moreira, Victor de Paula Coelho, Bruno Miranda Silva Lima, Elismauro Francisco de Mendonça, Diego Antonio Costa Arantes

{"title":"Oral low-grade fibromyxoid sarcoma: a case report","authors":"Cleiton Rone dos Santos Lima, Victor Hugo Lopes de Oliveira Moreira, Victor de Paula Coelho, Bruno Miranda Silva Lima, Elismauro Francisco de Mendonça, Diego Antonio Costa Arantes","doi":"10.1016/j.oooo.2025.01.007","DOIUrl":null,"url":null,"abstract":"<div><div>Low-grade fibromyxoid sarcoma is a rare malignant neoplasm of fibroblastic/myofibroblastic origin in the head and neck region. This lesion often arises in deep soft tissues with the potential for recurrence and late metastatic dissemination. A 23-year-old woman presented with a symptomatic swelling in the left posterior maxilla, evolving over 2 months, with an erythematous, ulcerated surface and evident telangiectasia. Computed tomography showed a hypodense osteolytic lesion located between tooth 27 and the maxillary tuberosity, with undefined borders and involvement of the left maxillary sinus. An incisional biopsy was performed, and histological analysis revealed a fibromyxoid neoplasm. Immunohistochemical staining was positive for AML, SATB2, Vimentin, and negative for SOX10, CD34, S100, Desmin. Considering both analyses, the final microscopic diagnosis was low-grade fibromyxoid sarcoma. The patient underwent surgical removal of the lesion, and after 12 months of clinical and radiographic follow-up, there are no signs of recurrence.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e1"},"PeriodicalIF":2.0000,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212440325000100","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Low-grade fibromyxoid sarcoma is a rare malignant neoplasm of fibroblastic/myofibroblastic origin in the head and neck region. This lesion often arises in deep soft tissues with the potential for recurrence and late metastatic dissemination. A 23-year-old woman presented with a symptomatic swelling in the left posterior maxilla, evolving over 2 months, with an erythematous, ulcerated surface and evident telangiectasia. Computed tomography showed a hypodense osteolytic lesion located between tooth 27 and the maxillary tuberosity, with undefined borders and involvement of the left maxillary sinus. An incisional biopsy was performed, and histological analysis revealed a fibromyxoid neoplasm. Immunohistochemical staining was positive for AML, SATB2, Vimentin, and negative for SOX10, CD34, S100, Desmin. Considering both analyses, the final microscopic diagnosis was low-grade fibromyxoid sarcoma. The patient underwent surgical removal of the lesion, and after 12 months of clinical and radiographic follow-up, there are no signs of recurrence.

查看原文本刊更多论文

口腔低级别纤维黏液样肉瘤1例

低级别纤维黏液样肉瘤是一种罕见的头颈部纤维母细胞/肌纤维母细胞恶性肿瘤。这种病变通常发生在深部软组织，有复发和晚期转移传播的可能。23岁女性，左后上颌骨出现症状性肿胀，持续2个多月，伴有红斑、溃疡表面和明显的毛细血管扩张。计算机断层扫描显示位于第27颗牙齿和上颌结节之间的低密度溶骨性病变，边界不明确，并累及左上颌窦。行切口活检，组织学分析显示为纤维黏液样肿瘤。免疫组化染色AML、SATB2、Vimentin阳性，SOX10、CD34、S100、Desmin阴性。综合两种分析，最终的显微镜诊断为低级别纤维黏液样肉瘤。患者接受手术切除病变，经过12个月的临床和影像学随访，无复发迹象。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.