Surgical excision of large myoepithelioma in the palate

IF 1.9 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.032

Fernanda Luiza Araújo de Lima Castro, Henrique Bemfica de Faria Freitas, Sérgio Antonucci Amaral, Renata Gonçalves Resende, Maria Cássia Ferreira Aguiar, Patrícia Carlos Caldeira, Júlio César Tanos Lacerda

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Abstract

A 30-year-old female presented to the hospital with an extensive tumoral lesion on the palate, with an evolution of 20 years, causing dysphagia and difficulty in speaking. Incisional biopsy revealed a fragment of nonencapsulated neoplasm with proliferation of myoepithelial cells, forming cellular cords. The cells had large and eosinophilic cytoplasm and rounded nuclei displaced to the periphery, configuring a plasmacytoid morphology. The stroma of the lesion was composed of fibrous connective tissue, sometimes with a myxomatous appearance. The diagnosis was compatible with myoepithelioma. She was submitted to surgery under general anesthesia for conservative surgical enucleation of the lesion. To cover the raw area, a double-layer acellular dermal matrix was used, composed of bovine collagen internally and silicone externally, which was removed 3 weeks after surgery. After removal, a granulation tissue was observed, later giving way to the epithelial tissue of the palate. The patient is on regular follow-up with no abnormalities.

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上颚大肌上皮瘤的手术切除

患者为30岁女性，上颚大面积肿瘤病变，发展20年，导致吞咽困难和说话困难。切口活检显示一段未包膜的肿瘤，伴有肌上皮细胞增生，形成细胞索。细胞具有大的嗜酸性细胞质，细胞核向周围移位，呈浆细胞样形态。病变间质由纤维结缔组织组成，有时呈黏液瘤样。诊断符合肌上皮瘤。患者在全麻下接受保守性手术切除病灶。为了覆盖裸区，使用双层脱细胞真皮基质，内部由牛胶原蛋白组成，外部由硅胶组成，术后3周取出。切除后，观察到肉芽组织，后来让位给上颚上皮组织。患者定期随访，未见异常。

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.