Oral carcinoma cuniculatum a rare entity: report of 3 cases

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.018

Javier Ignacio Gimenez, Maria de los Angeles Castrillo, Gabriela Acosta Haab, Gloria Irunigarro, Claudia Giacco, Verónica Flück

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Abstract

Carcinoma cuniculatum (CC) is a rare epithelial neoplasm, representing an unusual variety of squamous cell carcinoma (SCC). Histologically it is characterized by deep penetrating sinuses containing keratotic debris, making it susceptible to underdiagnosis. We present 3 cases seen during 2017-2023. They presented clinically as tumor lesions, fistulizing, and superficial blood vessels. The ages of the patients were 13, 70, and 80 years and the locations were jaw, upper maxilla, and trigone respectively. Multiple partial biopsies were performed, with CC not being the initial diagnosis. The definitive diagnosis was reached based on data collected from the anamnesis, clinical examination, histopathological and imaging analysis. The infrequency and the absence of cytological anaplasia, make CC susceptible to multiple negative biopsies and misdiagnosis. We emphasize clinical examination and anamnesis, together with the need to form work teams as a facilitating tool to establish the diagnosis.

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口腔癌是一种罕见的疾病：附3例报告

鳞状细胞癌（CC）是一种罕见的上皮性肿瘤，代表了鳞状细胞癌（SCC）的一种不同寻常的类型。组织学上，它的特点是深穿透性鼻窦含有角化碎片，使其容易误诊。我们报告了2017-2023年期间发生的3例病例。临床表现为肿瘤病变、瘘管和浅表血管。患者年龄分别为13岁、70岁和80岁，发病部位分别为上颌、上颌和三角区。进行了多次部分活检，CC不是最初的诊断。明确的诊断是根据收集的数据从记忆，临床检查，组织病理学和影像学分析。由于细胞学发育不全的罕见和缺乏，使得CC容易出现多次阴性活检和误诊。我们强调临床检查和记忆，同时需要组建工作小组，作为建立诊断的便利工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.