Josefina Martínez-Ramírez, Sibele Nascimento de Aquino, Hélen Kaline Farias Bezerra, Mario Fernando de Góes, Alan Roger Santos-Silva, Pablo Agustin Vargas, Márcio Ajudarte Lopes
{"title":"Unusual gingival reaction related to foreign body hydroxyapatite: a case report","authors":"Josefina Martínez-Ramírez, Sibele Nascimento de Aquino, Hélen Kaline Farias Bezerra, Mario Fernando de Góes, Alan Roger Santos-Silva, Pablo Agustin Vargas, Márcio Ajudarte Lopes","doi":"10.1016/j.oooo.2025.01.017","DOIUrl":null,"url":null,"abstract":"<div><div>A 56-year-old woman was referred for evaluation and management of 2 asymptomatic vestibular gingival lesions in the areas of both upper lateral incisors. These 2 teeth were missing, and the areas were rehabilitated with dental implants and crowns. The patient reported that was previously treated in another service with systematic antibiotics and antiseptic mouthwash without resolution. She denied tobacco and alcohol use and her medical history includes a stroke medicated with clopidogrel. Clinical examination revealed 2 nodular lesions with erythematous and whitish areas on the marginal gingiva, with approximately 1 cm each. Cone beam computed tomography revealed extraosseous hyperdense particles along the bilateral buccal cortical bone of the dental implants. Microscopic examination showed intense chronic inflammation associated with numerous birefringent structures with rectangular and triangular shapes immediately subjacent to the epithelium. Energy-dispersive X-ray analysis revealed calcium and phosphate as the main elements of the foreign body, allowing comparison with pure hydroxyapatite to confirm the similarity in composition. The case is especially unique due to the identification of an enlarged gingival reaction to hydroxyapatite.</div></div>","PeriodicalId":49010,"journal":{"name":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","volume":"139 5","pages":"Page e3"},"PeriodicalIF":2.0000,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Surgery Oral Medicine Oral Pathology Oral Radiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212440325000203","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
A 56-year-old woman was referred for evaluation and management of 2 asymptomatic vestibular gingival lesions in the areas of both upper lateral incisors. These 2 teeth were missing, and the areas were rehabilitated with dental implants and crowns. The patient reported that was previously treated in another service with systematic antibiotics and antiseptic mouthwash without resolution. She denied tobacco and alcohol use and her medical history includes a stroke medicated with clopidogrel. Clinical examination revealed 2 nodular lesions with erythematous and whitish areas on the marginal gingiva, with approximately 1 cm each. Cone beam computed tomography revealed extraosseous hyperdense particles along the bilateral buccal cortical bone of the dental implants. Microscopic examination showed intense chronic inflammation associated with numerous birefringent structures with rectangular and triangular shapes immediately subjacent to the epithelium. Energy-dispersive X-ray analysis revealed calcium and phosphate as the main elements of the foreign body, allowing comparison with pure hydroxyapatite to confirm the similarity in composition. The case is especially unique due to the identification of an enlarged gingival reaction to hydroxyapatite.
期刊介绍:
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.