Management of medication-induced gingival overgrowth in a hypertensive patient: a case report

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.041

Leticia Beatriz da Cruz Santos, Amanda Feitoza da Silva, Claudia Rebecca Costa Cavalcante Silva, Matheus Santos Mafra Barbosa, Mariana Bitu Ramos-Pinto, Lais Christina Pontes de Espindola, Thalwylla Reiler Moratodos Reis Moreira

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Abstract

Gingival overgrowth can arise from inflammatory factors related to biofilm or specific medications, including anticonvulsants, immunosuppressants, and calcium channel blockers. We present a case of medication-induced gingival overgrowth associated with amlodipine. A 40-year-old male patient presented with complaints of altered gingival contour after 8 months of initiating amlodipine treatment for hypertension. Upon clinical examination, increased growth of gingival interdental papillae was observed, along with the presence of pseudopockets upon periodontal probing. Initial periodontal treatment was followed by gingivectomy and gingivoplasty. Post-treatment, the patient was referred to a cardiologist to evaluate the possibility of changing medication to prevent recurrence. After 60 days of follow-up, the periodontal condition was deemed satisfactory. Medication-induced gingival overgrowth is a common adverse effect in certain medication groups, and gingival plastic surgery may be necessary to restore physiological gingival contour, thereby improving patient function and aesthetics.

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高血压患者药物性牙龈增生的处理：1例报告

牙龈过度生长可由与生物膜或特定药物相关的炎症因子引起，包括抗惊厥药、免疫抑制剂和钙通道阻滞剂。我们提出一个与氨氯地平相关的药物诱导的牙龈过度生长的病例。一位40岁男性患者在开始氨氯地平治疗高血压8个月后，以牙龈轮廓改变主诉。经临床检查，观察到牙龈牙间乳头的生长增加，牙周探查时出现假袋。最初的牙周治疗之后是牙龈切除术和牙龈成形术。治疗后，患者被转介给心脏病专家，以评估改变药物以防止复发的可能性。随访60天后，牙周状况满意。药物引起的牙龈过度生长是某些药物组常见的不良反应，可能需要进行牙龈整形手术以恢复生理牙龈轮廓，从而改善患者的功能和美观。

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.