Oral Kaposis sarcoma report of 4 cases

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.060

Yuri Kalinin, Vanessa Cristina de Branco Gonçalves, Ivan José Correia-Neto, Suellen Vieira do Nascimento, Lucas Lacerda de Souza

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引用次数: 0

Abstract

Oral Kaposi's Sarcoma (KS) presents a significant diagnostic challenge and is an important indicator of HIV/AIDS. This study aims to present a case series involving 4 male patients with a mean age of 28.5 years (range 22-39). The patients exhibited reddish, ulcerated, and bleeding lesions on the hard palate and gingiva, along with disseminated lesions. Incisional biopsies revealed spindle cell proliferation and slit-like vascular spaces, with immunohistochemistry positive for CD34 and HHV-8 markers, confirming the diagnosis of KS. For 2 patients, oral KS was the initial sign of HIV infection, which was also indicated by increased viral loads and decreased CD4/T cell counts. All patients were referred for treatment and have been under follow-up for an average of 30.5 months (range 2-48). This highlights the importance of recognizing oral KS as an early indicator of HIV and advocates for a comprehensive, multidisciplinary management approach to systemic diseases.

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.