Secondary oral syphilis mimicking aphthous ulceration in an adolescent: a case report

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.064

Thaís Xavier Pereira da Silva, Janete Dias Almeida, Luis Felipe das Chagas e Silva de Carvalho, Monica Ghislaine Oliveria Alves

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引用次数: 0

Abstract

A 14-year-old female patient presented with complaints of painful ulcers that first appeared on her tongue 2 months prior. The patient reported having used melaleuca, triamcinolone acetonide, and nystatin with no improvement. Clinically, multiple varying-sized well-defined plaques with ulcerated areas were observed. The lesions were primarily located on the lateral border of the tongue bilaterally and the upper and lower lips mucosa. Diagnostic considerations included syphilis, vitamin B12 deficiency, and major aphthous ulcer. Subsequent testing revealed positive results for VDRL and FTA-ABS, confirming the diagnosis of secondary syphilis. The patient was then referred to an infectious disease specialist for treatment. Syphilis poses a significant public health challenge globally, with increasing incidence rates, particularly among younger populations. The diagnosis of syphilis can be complex due to the overlapping of clinical manifestations with other conditions, in addition to the serious issue of self-medication. Careful evaluation is necessary for accurate diagnosis and treatment.

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一名 14 岁的女性患者主诉她的舌头在两个月前首次出现疼痛性溃疡。患者称曾使用美白芷、曲安奈德和硝酸酯类药物，但效果不佳。临床观察发现，患者舌头上出现多个大小不一、界限清晰的斑块，并伴有溃疡。病变主要位于双侧舌外侧缘和上下唇粘膜。诊断考虑因素包括梅毒、维生素 B12 缺乏症和重度阿弗他溃疡。随后的检测显示 VDRL 和 FTA-ABS 阳性，确诊为继发性梅毒。患者随后被转诊到传染病专科接受治疗。梅毒是全球公共卫生面临的重大挑战，发病率不断上升，尤其是在年轻人群中。由于梅毒的临床表现与其他疾病重叠，再加上自我用药这一严重问题，梅毒的诊断可能非常复杂。为了准确诊断和治疗，有必要进行仔细评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.