Patients aged 80 years and older have an equal improvement in joint-specific outcome health related quality of life and level of satisfaction when compared to those aged 65–75 years old undergoing knee arthroplasty

IF 1.6 4区 医学 Q3 ORTHOPEDICS
Knee Pub Date : 2025-03-13 DOI:10.1016/j.knee.2025.02.017
Gregory Hodgson , Samantha Jones , Jad Wehbe , Irrum Afzal , Nick D Clement , Deiary F Kader
{"title":"Patients aged 80 years and older have an equal improvement in joint-specific outcome health related quality of life and level of satisfaction when compared to those aged 65–75 years old undergoing knee arthroplasty","authors":"Gregory Hodgson ,&nbsp;Samantha Jones ,&nbsp;Jad Wehbe ,&nbsp;Irrum Afzal ,&nbsp;Nick D Clement ,&nbsp;Deiary F Kader","doi":"10.1016/j.knee.2025.02.017","DOIUrl":null,"url":null,"abstract":"<div><h3>Aims</h3><div>To assess functional outcomes, health-related quality-of-life (HRQoL), and satisfaction at 1-year following knee arthroplasty (KA) in patients aged ≥80 compared to those aged 65–75-years when adjusting for confounding factors.</div></div><div><h3>Methods</h3><div>A single-centre retrospective cohort study was performed using data from 2010 to 2020. Demographic data, length of stay (LOS), preoperative and 1-year postoperative EuroQol (EQ-5D and EQ-VAS), Oxford Knee Score (OKS) and Outcome Satisfaction (OS) were recorded. Patients aged ≥80 were compared to a control group aged 65–75-years. Regression analyses were performed to assess the independent association of age group after adjusting for confounding factors.</div></div><div><h3>Results</h3><div>Compared to the 65–75-year group (<em>n</em> = 7525) the ≥80-year group (<em>n</em> = 2966) had greater comorbidity (<em>p</em> &lt; 0.001), worse preoperative OKS (<em>p</em> &lt; 0.001) and EQ-VAS (<em>p</em> = 0.012). Postoperatively both groups had clinically and statistically significant (<em>p</em> &lt; 0.001) improvements in OKS, EQ-5D and EQ-VAS. There was no difference in improvement in OKS (mean difference (<em>p</em> = 0.081) or OS (<em>p</em> = 0.203) between the groups. However, the ≥80-year group had less of an improvement in EQ-5D (<em>p</em> = 0.047) and EQ-VAS (<em>p</em> = 0.007), but these were not clinically meaningful. However, when adjusting for confounding variables there were no differences in improvement in OKS (<em>p</em> = 0.372), EQ-5D (<em>p</em> = 0.703), and EQ-VAS (<em>p</em> = 0.283), or OS (<em>p</em> = 0.829) between the groups. The ≥80-year group was independently associated with a longer LOS (95% CI 0.3–0.8, <em>p</em> &lt; 0.001) when adjusting for confounding factors.</div></div><div><h3>Conclusions</h3><div>Patients ≥80-years had clinically significant improvements in joint-specific outcome and HRQoL and OS equal to those aged 65–75-years following KA. The ≥80 group had a longer mean LOS of half a day.</div></div>","PeriodicalId":56110,"journal":{"name":"Knee","volume":"54 ","pages":"Pages 209-216"},"PeriodicalIF":1.6000,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Knee","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0968016025000316","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0

Abstract

Aims

To assess functional outcomes, health-related quality-of-life (HRQoL), and satisfaction at 1-year following knee arthroplasty (KA) in patients aged ≥80 compared to those aged 65–75-years when adjusting for confounding factors.

Methods

A single-centre retrospective cohort study was performed using data from 2010 to 2020. Demographic data, length of stay (LOS), preoperative and 1-year postoperative EuroQol (EQ-5D and EQ-VAS), Oxford Knee Score (OKS) and Outcome Satisfaction (OS) were recorded. Patients aged ≥80 were compared to a control group aged 65–75-years. Regression analyses were performed to assess the independent association of age group after adjusting for confounding factors.

Results

Compared to the 65–75-year group (n = 7525) the ≥80-year group (n = 2966) had greater comorbidity (p < 0.001), worse preoperative OKS (p < 0.001) and EQ-VAS (p = 0.012). Postoperatively both groups had clinically and statistically significant (p < 0.001) improvements in OKS, EQ-5D and EQ-VAS. There was no difference in improvement in OKS (mean difference (p = 0.081) or OS (p = 0.203) between the groups. However, the ≥80-year group had less of an improvement in EQ-5D (p = 0.047) and EQ-VAS (p = 0.007), but these were not clinically meaningful. However, when adjusting for confounding variables there were no differences in improvement in OKS (p = 0.372), EQ-5D (p = 0.703), and EQ-VAS (p = 0.283), or OS (p = 0.829) between the groups. The ≥80-year group was independently associated with a longer LOS (95% CI 0.3–0.8, p < 0.001) when adjusting for confounding factors.

Conclusions

Patients ≥80-years had clinically significant improvements in joint-specific outcome and HRQoL and OS equal to those aged 65–75-years following KA. The ≥80 group had a longer mean LOS of half a day.
目的评估膝关节置换术(KA)后 1 年的功能结果、健康相关生活质量(HRQoL)和满意度,并与 65-75 岁的患者进行比较,同时对混杂因素进行调整。研究记录了人口统计学数据、住院时间(LOS)、术前和术后1年的EuroQol(EQ-5D和EQ-VAS)、牛津膝关节评分(OKS)和结果满意度(OS)。年龄≥80岁的患者与65-75岁的对照组进行了比较。结果与 65-75 岁组(n = 7525)相比,≥80 岁组(n = 2966)的合并症较多(p < 0.001),术前 OKS(p < 0.001)和 EQ-VAS (p = 0.012)较差。术后,两组患者的 OKS、EQ-5D 和 EQ-VAS 均有临床和统计意义上的显著改善(p < 0.001)。两组在 OKS(平均差异(p = 0.081)或 OS(p = 0.203)方面的改善没有差异。然而,≥80 岁组在 EQ-5D(p = 0.047)和 EQ-VAS (p = 0.007)方面的改善较小,但这些改善并无临床意义。然而,在对混杂变量进行调整后,各组之间在 OKS(p = 0.372)、EQ-5D(p = 0.703)和 EQ-VAS (p = 0.283)或 OS(p = 0.829)的改善方面没有差异。结论与 65-75 岁的患者相比,≥80 岁的患者在接受 KA 治疗后,关节特异性结果、HRQoL 和 OS 均有显著的临床改善。≥80岁组患者的平均住院日延长了半天。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Knee
Knee 医学-外科
CiteScore
3.80
自引率
5.30%
发文量
171
审稿时长
6 months
期刊介绍: The Knee is an international journal publishing studies on the clinical treatment and fundamental biomechanical characteristics of this joint. The aim of the journal is to provide a vehicle relevant to surgeons, biomedical engineers, imaging specialists, materials scientists, rehabilitation personnel and all those with an interest in the knee. The topics covered include, but are not limited to: • Anatomy, physiology, morphology and biochemistry; • Biomechanical studies; • Advances in the development of prosthetic, orthotic and augmentation devices; • Imaging and diagnostic techniques; • Pathology; • Trauma; • Surgery; • Rehabilitation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信