Bone mechanical behavior around dental implants: Densification and deformation follow-up by in-situ computed tomography

IF 3.3 2区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of the Mechanical Behavior of Biomedical Materials Pub Date : 2025-03-06 DOI:10.1016/j.jmbbm.2025.106966

Laura Preiss , Rémy Gauthier , Hervé Richard , Loïc Courtois , Anne-Lise Chopard-Lallier , Damien Fabrègue , Jérôme Chevalier , Nicolas Courtois

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Abstract

The state of bone tissue around dental implants is a crucial factor influencing their early clinical outcomes. Currently, this state is mainly defined by its primary stability, both in terms of biomechanical analysis and clinically. The clinical methods used for quantifying this stability—such as the Implant Stability Quotient (ISQ) and Insertion Torque (IT)—are indirect measures. While these methods provide insights into the overall mechanical behavior of the bone-implant system, they do not account for the impact of implant morphology on the surrounding bone. The method presented here aims to analyze the peri-implant bone using image analysis and volume correlation techniques combined with computed tomography to assess the bone strain field and densification resulting from dental implant placement. The study utilized two types of implants with distinct designs—one cylindrical and the other self-tapping—on five iliac crest bone samples harvested from butcher pigs. The results indicated that the self-tapping implant caused significantly greater bone densification near the implant compared to the cylindrical one (46% of densification in the first 30 μm, against 21% for cylindrical implant). Additionally, the volume of strained peri-implant bone appeared to be larger for the self-tapping implant (38% of the volume was mechanically affected above 0,5% VM strains for self-tapping implant, against 31% for the cylindrical implant), though this difference was not statistically significant. Furthermore, established descriptors from the literature struggled to effectively differentiate between the two implant types. Despite the study's limitations, the proposed method shows promise for distinguishing implants based on the densification and deformation of peri-implant bone, and can serve as a complementary approach to standard ISQ and IT measurements.

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牙科植入物周围的骨机械行为：通过原位计算机断层扫描跟踪骨质致密化和变形情况

种植体周围骨组织的状态是影响其早期临床结果的关键因素。目前，无论是生物力学分析还是临床，这种状态主要由其初级稳定性来定义。用于量化这种稳定性的临床方法，如种植体稳定商（ISQ）和插入扭矩（IT），都是间接测量方法。虽然这些方法提供了对骨-种植体系统整体力学行为的见解，但它们不能解释种植体形态对周围骨的影响。本文提出的方法旨在利用图像分析和体积相关技术结合计算机断层扫描来分析种植体周围的骨，以评估牙种植体放置引起的骨应变场和致密化。这项研究使用了两种不同设计的植入物——一种是圆柱形的，另一种是自敲式的——在5个从屠宰猪身上采集的髂骨样本上。结果表明，自攻种植体在种植体附近的骨密度显著高于圆柱形种植体（前30 μm的密度为46%，而圆柱形种植体的密度为21%）。此外，自攻种植体的种植周围骨的应变体积似乎更大（自攻种植体的体积在0.5% VM应变以上受到机械影响的比例为38%，而圆柱形种植体为31%），尽管这种差异没有统计学意义。此外，从文献中建立的描述符难以有效区分两种种植体类型。尽管该研究存在局限性，但该方法有望根据种植体周围骨的致密化和变形来区分种植体，并且可以作为标准ISQ和IT测量的补充方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Mechanical Behavior of Biomedical Materials 工程技术-材料科学：生物材料

CiteScore

7.20

自引率

7.70%

发文量

505

审稿时长

46 days

期刊介绍： The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.