Short and long-term side effects of eligible COVID-19 vaccines in Saudi Arabia, Southern Region, 2023

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2025-03-07 DOI:10.1016/j.cegh.2025.101975

Arif Ahmed AL Qahtani , Hassan Ahmed Korairi , Mohammad Ali Alzaedy , Moshabab Abdallah Al Nasher , Ali Saad Alshahrani , Noha Saleh Mohamed , Omar Mohammed Alzahrani , Khattab mohammed Aboudi Ahamed , Jamilah Hadi Al Ali , Mohammed Ahmed Alqahtani , Ahmed Youssef Abouelyazid

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引用次数: 0

Abstract

The mainstay of COVID-19 prevention is vaccination. Nonetheless, ongoing monitoring of the short- or long-term side effects of different vaccination types is required. According to post-marketing research the types and rates of adverse events reported by vaccine recipients have varied much. Hence, adverse effects should be appropriately monitored as vaccines become more widely available worldwide.

Objectives

a study was designed to assess the possible side effects of COVID-19 vaccines either on a short (up to 3 days) or long-term (up to 2 months) scale.

Methods

A hospital-based cross-sectional study with an analytical component was conducted to determine the prevalence and to compare side effects among the vaccinated population. Data were collected during three months at outpatient clinics in Southern Region, Saudi Arabia. A validated questionnaire was used to cover the participants’ demographic data, medical anamneses, COVID-19-related anamneses, and possible side effects.

Results

The most common side effects were 79.9 % myalgia, 78.1 % fever, 57.3 % bone pain, 56 % fatigue, 54.9 % joint pain, 48.7 % injection site pain, 40.1 % arm numbness, 37.8 % headache, 36.2 % low back pain, 18 % common cold, 14.3/5 cough, dizziness, 14.1 % shortness of breath, 11.2 % sneezing and 10.7 % sore throat.

Conclusions

A statistically significant difference is detected between different types of vaccine as regards most side effects., Overweight and obese, subjects with education higher than secondary, presence of comorbidities, previous COVID-19 infection, and Pfizer vaccination recipients were the predictors of developing post-vaccination side effects. Common symptoms that are also associated with other vaccines.

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2023年沙特阿拉伯南部地区符合条件的COVID-19疫苗的短期和长期副作用

预防COVID-19的主要手段是疫苗接种。尽管如此，仍需要对不同类型疫苗的短期或长期副作用进行持续监测。根据上市后的研究，疫苗接种者报告的不良事件的类型和比率差别很大。因此，随着疫苗在世界范围内得到更广泛的使用，应适当监测不良反应。目的：本研究旨在评估COVID-19疫苗短期（最长3天）或长期（最长2个月）可能产生的副作用。方法采用一项以医院为基础的横断面研究，以确定疫苗接种人群的患病率并比较其副作用。在沙特阿拉伯南部地区的门诊诊所收集了三个月的数据。使用一份经过验证的问卷来涵盖参与者的人口统计数据、医疗记录、与covid -19相关的记录和可能的副作用。结果最常见的不良反应为79.9%的肌痛、78.1%的发热、57.3%的骨痛、56%的疲劳、54.9%的关节痛、48.7%的注射部位痛、40.1%的手臂麻木、37.8%的头痛、36.2%的腰痛、18%的普通感冒、14.3/5咳嗽、头晕、14.1%的呼吸短促、11.2%的打喷嚏和10.7%的喉咙痛。结论不同类型疫苗的大部分毒副反应差异有统计学意义。超重和肥胖、受教育程度高于中学、存在合并症、既往COVID-19感染和辉瑞疫苗接种者是发生疫苗接种后副作用的预测因素。常见症状也与其他疫苗有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.