The Annual Incidence of Vascular Dementia and Other Dementias: A Population-Based Study in Eastern Finland.

IF 3.2 3区 医学 Q2 CLINICAL NEUROLOGY
Ada Tuominen, Virve Kärkkäinen, Viivi Jetsonen, Tuomas Selander, Olli Lappalainen, Pekka Jäkälä, Anne Koivisto
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Abstract

Introduction: Considering the globally growing population and the rising incidence of dementia, it is important to understand the proportion of dementia cases affected by vascular brain disease. We aimed to study the incidence of vascular dementia (VD) and other dementias in a defined population in Finland to better understand VD's contribution to the total incidence of dementias and to assess the sensitivity of their diagnostics.

Methods: We aimed to collect all dementia diagnoses made in Northern Savo, Finland, in 2020. The memory disorder diagnoses were identified using the International Classification Codes 10th Revision (ICD-10) diagnosis codes. Finally, we studied the diagnoses in relation to demographic data, focusing on VD.

Results: The total number of new diagnoses of dementia with a vascular component or vascular alone was 202, with 20 cases attributable to pure VD. The annual incidence of dementias with a vascular component in Northern Savo was 81.4 per 100,000 across the population and 310.8 per 100,000 in the age group of ≥65. In our study population, 23.8% of all incident dementia cases were associated with vascular disease.

Conclusion: According to our findings, dementia associated with vascular pathology has the second highest incidence after Alzheimer's disease, while pure VD is rarely diagnosed. Our findings align with previous international studies and a recent national registry study. Future studies with a prospective study setting, potentially incorporating extensive neuroimaging, would be critical in further understanding the epidemiology of VD.

血管性痴呆和其他痴呆的年发病率:芬兰东部一项基于人群的研究。
导读:考虑到全球人口的增长和痴呆发病率的上升,了解血管性脑疾病影响的痴呆病例的比例是很重要的。我们的目的是研究芬兰特定人群中血管性痴呆(VD)和其他痴呆的发病率,以更好地了解VD对痴呆总发病率的贡献,并评估其诊断的敏感性。方法:我们的目标是收集2020年芬兰北萨沃所有痴呆诊断。采用国际分类代码第10版(ICD-10)诊断代码对记忆障碍进行诊断。最后,我们研究了与人口统计学数据相关的诊断,重点是VD。结果:合并血管性痴呆或单纯血管性痴呆新诊断202例,单纯血管性痴呆20例。在北萨沃地区,血管性痴呆的年发病率为81.4 / 10万,在65岁年龄组中为310.8 / 10万。在我们的研究人群中,23.8%的痴呆病例与血管疾病相关。结论:根据我们的研究结果,痴呆合并血管病变是仅次于阿尔茨海默病(AD)的发病率第二高的疾病,而单纯的VD很少被诊断出来。我们的发现与之前的国际研究和最近的一项国家登记研究相一致。未来有前瞻性研究背景的研究,可能包括广泛的神经影像学,将对进一步了解VD的流行病学至关重要。
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来源期刊
Neuroepidemiology
Neuroepidemiology 医学-公共卫生、环境卫生与职业卫生
CiteScore
9.90
自引率
1.80%
发文量
49
审稿时长
6-12 weeks
期刊介绍: ''Neuroepidemiology'' is the only internationally recognised peer-reviewed periodical devoted to descriptive, analytical and experimental studies in the epidemiology of neurologic disease. The scope of the journal expands the boundaries of traditional clinical neurology by providing new insights regarding the etiology, determinants, distribution, management and prevention of diseases of the nervous system.
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