Johannes M Herold, Isaiah Selkridge, Allina A Nocon, Troy D Bornes, Thomas P Sculco, Alberto V Carli, Peter K Sculco
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引用次数: 0
Abstract
Background: The burden of revision total joint arthroplasty (rTJA) is increasing. Revision procedures are associated with an increased risk of perioperative complications. Obese patients undergoing rTJA may have a higher risk of wound complications due to their soft-tissue envelope. Closed-incision negative pressure wound therapy (ciNPWT) has been rigorously investigated for its effect on reducing wound complications, however, the literature is limited to primary total joint arthroplasty. The purpose of the current study was to investigate the association between ciNPWT and clinical outcomes for obese patients undergoing aseptic revision total hip and knee arthroplasty.
Methods: This was a retrospective study examining aseptic rTJA procedures from January 2017 to December 2021 at a high-volume institution. Patients were included if their body mass index (BMI) was > 35 and had a minimum follow-up of two years. The cohorts were rTJA procedures that used ciNPWT versus procedures without ciNPWT use. A total of 214 rTJA (Hip, n = 61; Knee, n = 153) patients qualified for analysis. After surgery, ciNPWT was applied on 130 (60.7%) patients (92 knees, 38 hips), and standard dressing was used on 84 (39.3%) patients (61 knees, 23 hips). There were no significant baseline differences between the groups. Outcomes evaluated were: (1) revision for infection; (2) superficial wound complications; (3) overall complications; (4) all-cause revision; and (5) all-cause readmissions. The association between ciNPWT use and outcomes was evaluated using Chi-square tests.
Results: When controlling for all variables, ciNPWT use was associated with significantly fewer revisions for infection (0.8 versus 8.3%), overall complications (3.8 versus 11.9%), all-cause revisions (3.1 versus 13.1%), and readmissions (10.8 versus 21.7%) compared to those who did not use ciNPWT. Secondary superficial wound complication-specific outcomes did not show significant differences.
Conclusion: To our knowledge, this study is the largest retrospective study to date examining the effect of ciNPWT on outcomes in obese aseptic revision rTJA patients. Our results demonstrated major benefits associated with the use of ciNPWT in obese patients undergoing aseptic rTJA in reference to infection-related revision, overall complications, all-cause revisions, and early readmission for any reason.
背景:翻修全关节置换术(rTJA)的负担正在增加。翻修手术与围手术期并发症的风险增加有关。肥胖患者接受rTJA可能有较高的风险伤口并发症,由于他们的软组织包膜。闭合切口负压伤口治疗(ciNPWT)在减少伤口并发症方面的作用已经得到了严格的研究,然而,文献仅限于初次全关节置换术。本研究的目的是调查接受无菌翻修全髋关节置换术的肥胖患者的ciNPWT与临床结果之间的关系。方法:这是一项回顾性研究,检查了2017年1月至2021年12月在一家高容量机构进行的无菌rTJA手术。如果患者的身体质量指数(BMI)为bbb35,且随访时间至少为两年,则纳入研究。队列是使用ciNPWT的rTJA手术和不使用ciNPWT的手术。共214例rTJA (Hip, n = 61;膝关节,n = 153)例患者符合分析条件。术后130例(60.7%)患者(92个膝关节,38个髋关节)使用了ciNPWT, 84例(39.3%)患者(61个膝关节,23个髋关节)使用了标准敷料。两组之间没有明显的基线差异。评估的结果是:(1)感染的修订;(2)浅表伤口并发症;(3)全身并发症;(4)全因修正;(5)全因再入院。使用卡方检验评估ciNPWT使用与预后之间的关系。结果:在控制所有变量的情况下,与不使用ciNPWT的患者相比,使用ciNPWT的患者在感染(0.8 vs 8.3%)、总并发症(3.8 vs 11.9%)、全因翻修(3.1 vs 13.1%)和再入院(10.8 vs 21.7%)方面的翻修率显著降低。继发性浅表伤口并发症特异性结局无显著差异。结论:据我们所知,这项研究是迄今为止最大的回顾性研究,旨在研究ciNPWT对肥胖无菌改造rTJA患者预后的影响。我们的研究结果表明,在接受无菌rTJA的肥胖患者中,使用ciNPWT在感染相关翻修、总体并发症、全因翻修和任何原因的早期再入院方面具有主要益处。
期刊介绍:
The Journal of Arthroplasty brings together the clinical and scientific foundations for joint replacement. This peer-reviewed journal publishes original research and manuscripts of the highest quality from all areas relating to joint replacement or the treatment of its complications, including those dealing with clinical series and experience, prosthetic design, biomechanics, biomaterials, metallurgy, biologic response to arthroplasty materials in vivo and in vitro.