Jian Xiao, Hong Gu, Jiaqing Zhang, Yuqian Xue, Yunyi Chen, Weizhong Zhu, Hong Zhang, Boyi Fan, Wenli Wang
{"title":"A Comprehensive Review of the Phytochemistry, Pharmacology and Other Applications of Euphorbiae Humifusae Herba.","authors":"Jian Xiao, Hong Gu, Jiaqing Zhang, Yuqian Xue, Yunyi Chen, Weizhong Zhu, Hong Zhang, Boyi Fan, Wenli Wang","doi":"10.3390/molecules30051094","DOIUrl":null,"url":null,"abstract":"<p><p>Euphorbiae Humifusae Herba (EHH) is a globally distributed plant commonly utilized in traditional Chinese medicine (TCM) and health food within China. The dried aerial parts of EHH are well-recognized as health foods for the management of diarrhea and other intestinal diseases. Known for its therapeutic effects, such as heat-clearing, detoxification, blood cooling, hemostasis, dampness, elimination, and jaundice relief, EHH has yielded 197 bioactive compounds identified to date, including terpenoids, flavonoids, phenolic acids, tannins, alkaloids, sterols, lactones, coumarins, and other constituents, with flavonoids and terpenoids, highlighting its wide-ranging pharmacological properties and medicinal significance. Despite its popularity in research, limited systematic and comprehensive information has been provided on the EHH. Therefore, we provide an in-depth overview of EHH, covering its botanical characteristics, traditional uses, phytochemical composition, pharmacological properties, and additional applications. Furthermore, it addresses the current challenges and limitations in modern research on EHH, offering critical perspectives to guide future studies in this field.</p>","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 5","pages":""},"PeriodicalIF":4.2000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901922/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecules","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.3390/molecules30051094","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Euphorbiae Humifusae Herba (EHH) is a globally distributed plant commonly utilized in traditional Chinese medicine (TCM) and health food within China. The dried aerial parts of EHH are well-recognized as health foods for the management of diarrhea and other intestinal diseases. Known for its therapeutic effects, such as heat-clearing, detoxification, blood cooling, hemostasis, dampness, elimination, and jaundice relief, EHH has yielded 197 bioactive compounds identified to date, including terpenoids, flavonoids, phenolic acids, tannins, alkaloids, sterols, lactones, coumarins, and other constituents, with flavonoids and terpenoids, highlighting its wide-ranging pharmacological properties and medicinal significance. Despite its popularity in research, limited systematic and comprehensive information has been provided on the EHH. Therefore, we provide an in-depth overview of EHH, covering its botanical characteristics, traditional uses, phytochemical composition, pharmacological properties, and additional applications. Furthermore, it addresses the current challenges and limitations in modern research on EHH, offering critical perspectives to guide future studies in this field.
期刊介绍:
Molecules (ISSN 1420-3049, CODEN: MOLEFW) is an open access journal of synthetic organic chemistry and natural product chemistry. All articles are peer-reviewed and published continously upon acceptance. Molecules is published by MDPI, Basel, Switzerland. Our aim is to encourage chemists to publish as much as possible their experimental detail, particularly synthetic procedures and characterization information. There is no restriction on the length of the experimental section. In addition, availability of compound samples is published and considered as important information. Authors are encouraged to register or deposit their chemical samples through the non-profit international organization Molecular Diversity Preservation International (MDPI). Molecules has been launched in 1996 to preserve and exploit molecular diversity of both, chemical information and chemical substances.