{"title":"Left- and right-side unilateral spatial neglect: Hemispheric differences.","authors":"Laura Veronelli, Giuseppe Vallar","doi":"10.1016/B978-0-443-15646-5.00025-7","DOIUrl":null,"url":null,"abstract":"<p><p>Neglect of one side of space, typically contralateral to a lesion of one cerebral hemisphere, is a multicomponent neurologic syndrome. In humans, left neglect after right brain damage is more frequent, severe, or both, than right neglect after left brain damage. Right neglect is behaviorally like left neglect. In the monkey, such a functional asymmetry is not present. In humans, left hemisphere-based spatial systems are weaker, likely due to the coexistence of language and spatial processes. This may account for the lateral asymmetry of neglect, which is present at birth. Except in a few patients, there is no global functional reversal of language and spatial cognition. Left brain-damaged patients often show both aphasia and right neglect, as many right brain-damaged patients with crossed aphasia show left neglect. Lateralized sensory stimulations temporarily improve both left and right neglect. Damage to the posterior parietal lobe (inferior parietal lobule), the temporo-parietal junction, the superior and middle temporal, and to the premotor and prefrontal cortices is associated with contralateral neglect; also, lesions in white matter fiber tracts and subcortical nuclei bring about neglect, with no definite left-right asymmetries.</p>","PeriodicalId":12907,"journal":{"name":"Handbook of clinical neurology","volume":"208 ","pages":"127-154"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Handbook of clinical neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/B978-0-443-15646-5.00025-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Neglect of one side of space, typically contralateral to a lesion of one cerebral hemisphere, is a multicomponent neurologic syndrome. In humans, left neglect after right brain damage is more frequent, severe, or both, than right neglect after left brain damage. Right neglect is behaviorally like left neglect. In the monkey, such a functional asymmetry is not present. In humans, left hemisphere-based spatial systems are weaker, likely due to the coexistence of language and spatial processes. This may account for the lateral asymmetry of neglect, which is present at birth. Except in a few patients, there is no global functional reversal of language and spatial cognition. Left brain-damaged patients often show both aphasia and right neglect, as many right brain-damaged patients with crossed aphasia show left neglect. Lateralized sensory stimulations temporarily improve both left and right neglect. Damage to the posterior parietal lobe (inferior parietal lobule), the temporo-parietal junction, the superior and middle temporal, and to the premotor and prefrontal cortices is associated with contralateral neglect; also, lesions in white matter fiber tracts and subcortical nuclei bring about neglect, with no definite left-right asymmetries.
期刊介绍：
The Handbook of Clinical Neurology (HCN) was originally conceived and edited by Pierre Vinken and George Bruyn as a prestigious, multivolume reference work that would cover all the disorders encountered by clinicians and researchers engaged in neurology and allied fields. The first series of the Handbook (Volumes 1-44) was published between 1968 and 1982 and was followed by a second series (Volumes 45-78), guided by the same editors, which concluded in 2002. By that time, the Handbook had come to represent one of the largest scientific works ever published. In 2002, Professors Michael J. Aminoff, François Boller, and Dick F. Swaab took on the responsibility of supervising the third (current) series, the first volumes of which published in 2003. They have designed this series to encompass both clinical neurology and also the basic and clinical neurosciences that are its underpinning. Given the enormity and complexity of the accumulating literature, it is almost impossible to keep abreast of developments in the field, thus providing the raison d''être for the series. The series will thus appeal to clinicians and investigators alike, providing to each an added dimension. Now, more than 140 volumes after it began, the Handbook of Clinical Neurology series has an unparalleled reputation for providing the latest information on fundamental research on the operation of the nervous system in health and disease, comprehensive clinical information on neurological and related disorders, and up-to-date treatment protocols.
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