Diagnosis of fictitious disorder by proxy in a sibling by administration of anti-vitamin K in an 8-year-old child.

IF 1.5 4区 医学 Q2 MEDICINE, LEGAL
Cindy Verney, Alice Matheux, Philippe Savard, Emmanuel De Maistre, Joseph Berthier, Bruno Begue, Pascal Guerard, Caroline Rey-Salmon, Sylvie Bernardini, Mélanie Loiseau
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Abstract

Fictitious disorder by proxy (FDP) is characterized by an adult, often a parent, alleging or fabricating symptoms in a child to induce repeated diagnostic tests or treatments. This form of abuse is particularly serious and difficult to diagnose. Worldwide, it is estimated that 0.5 to 1.2 per 100,000 children are abused in this way every year. We report the case of FDP in an 8-year-old child who presented with coagulation disorders secondary to the unknowing administration of Acenocoumarin. His parents had requested seven medical consultations over a six-month period. The parents systematically reported a coagulation pathology (factor VII deficiency), prompting further investigations and treatment. Biological tests showed deficiencies of vitamin K-dependent coagulation factors, raising suspicion of vitamin K antagonists (VKA) use. Toxicological tests revealed the presence of Acenocoumarin in the child's blood three times, at levels of 0.15 mg/L; 0.06 mg/L and 0.43 mg/L. The biological abnormalities corrected spontaneously after the child was hospitalized. A family investigation led to the diagnosis of medical child abuse in the child's older sister, who presented bleeding. The severity and recurrence of this syndrome correlated with the role that caregivers play in this type of abuse deserves our full attention to prevent and manage it as effectively as possible.

在一个8岁的孩子的抗维生素K管理的兄弟姐妹代理诊断虚构障碍。
虚构代理障碍(FDP)的特点是一个成年人,通常是父母,声称或捏造儿童的症状,以诱导反复的诊断测试或治疗。这种形式的虐待特别严重,难以诊断。在世界范围内,估计每年每10万名儿童中有0.5至1.2人受到这种虐待。我们报告的病例FDP在一个8岁的儿童谁提出凝血功能障碍继发于不明给药阿塞诺香豆素。他的父母在六个月期间要求进行七次医疗咨询。父母系统地报告了凝血病理(因子VII缺乏),促使进一步的调查和治疗。生物试验显示缺乏维生素K依赖性凝血因子,引起对维生素K拮抗剂(VKA)使用的怀疑。毒理学测试显示,三次在儿童血液中发现了阿塞诺香豆素,含量为0.15毫克/升;0.06 mg/L和0.43 mg/L。儿童住院后,生理异常自行纠正。一项家庭调查显示,孩子的姐姐被诊断为医疗虐待儿童,并出现出血。这种综合症的严重程度和复发与照顾者在这类虐待中所起的作用有关,值得我们充分注意,以尽可能有效地预防和管理它。
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来源期刊
Forensic Science, Medicine and Pathology
Forensic Science, Medicine and Pathology MEDICINE, LEGAL-PATHOLOGY
CiteScore
3.90
自引率
5.60%
发文量
114
审稿时长
6-12 weeks
期刊介绍: Forensic Science, Medicine and Pathology encompasses all aspects of modern day forensics, equally applying to children or adults, either living or the deceased. This includes forensic science, medicine, nursing, and pathology, as well as toxicology, human identification, mass disasters/mass war graves, profiling, imaging, policing, wound assessment, sexual assault, anthropology, archeology, forensic search, entomology, botany, biology, veterinary pathology, and DNA. Forensic Science, Medicine, and Pathology presents a balance of forensic research and reviews from around the world to reflect modern advances through peer-reviewed papers, short communications, meeting proceedings and case reports.
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