Provincial Variation in Adherence to Breast Cancer Screening in Canada: Evidence From the Canadian Partnership for Tomorrow's Health

IF 2.9 2区医学 Q2 ONCOLOGY

Cancer Medicine Pub Date : 2025-03-13 DOI:10.1002/cam4.70543

M. Darvishian, A. Moustaqim-Barrette, P. Awadalla, P. Bhatti, P. Broet, R. A. Murphy, K. Skead, R. Urquhart, J. Vena, T. J. B. Dummer

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引用次数: 0

Abstract

Background

Breast cancer is the most commonly diagnosed cancer among women in Canada. Screening is effective in reducing breast cancer mortality through early cancer detection. However, data on individual social and medical characteristics contributing to variation in adherence to screening is limited.

Methods

Using multivariable logistic regression, we analyzed self-reported questions on engagement in screening mammography from five regions of the Canadian Partnership for Tomorrow's Health (CanPath), including the BC Generations Project (BCGP), Alberta's Tomorrow Project (ATP), the Ontario Health Study (OHS), Quebec's CARTaGENE, and the Atlantic Partnership for Tomorrow's Health Study (Atlantic PATH).

Results

The study population included 79,986 and 46,907 individuals aged 50–74 and 40–49 years at study enrollment, respectively. Most participants self-reported undergoing screening mammography less than 2 years from study enrollment, ranging from 77.8% in OHS to 86.3% in BCGP. Factors significantly associated with a lower odd of ever undergoing screening mammography were lower household income, being single/never married, current daily smoking, poor self-perceived health, no history of breast feeding, and ≥ 24 months since last routine medical check-up by a doctor or nurse. Among women aged 40–49 years with a first-degree family history of breast cancer (N = 4212 [8.9%]), the likelihood of ever being screened varied by region and was significantly lower among individuals with post menopause and more than 12 months since last medical check-up.

Conclusion

Factors associated with screening adherence that were identified in this study namely household income, self-perceived health, and routine medical check-ups should be considered as potential factors for targeting undeserved communities and increasing engagement in screening at both provincial and national levels. The observed variation in mammography among women aged 40 to 49 years with family history of breast cancer, may inform the current guidelines for potential benefits of early screening initiation.

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来源期刊

Cancer Medicine ONCOLOGY-

CiteScore

5.50

自引率

2.50%

发文量

907

审稿时长

19 weeks

期刊介绍： Cancer Medicine is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research from global biomedical researchers across the cancer sciences. The journal will consider submissions from all oncologic specialties, including, but not limited to, the following areas: Clinical Cancer Research Translational research ∙ clinical trials ∙ chemotherapy ∙ radiation therapy ∙ surgical therapy ∙ clinical observations ∙ clinical guidelines ∙ genetic consultation ∙ ethical considerations Cancer Biology: Molecular biology ∙ cellular biology ∙ molecular genetics ∙ genomics ∙ immunology ∙ epigenetics ∙ metabolic studies ∙ proteomics ∙ cytopathology ∙ carcinogenesis ∙ drug discovery and delivery. Cancer Prevention: Behavioral science ∙ psychosocial studies ∙ screening ∙ nutrition ∙ epidemiology and prevention ∙ community outreach. Bioinformatics: Gene expressions profiles ∙ gene regulation networks ∙ genome bioinformatics ∙ pathwayanalysis ∙ prognostic biomarkers. Cancer Medicine publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper.